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Roberta E Burden

Explore the profile of Roberta E Burden including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 496
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Recent Articles
1.
Alsad A, Greene M, Tayyem M, Elmore B, Abed A, Burden R, et al.
Int J Pharm . 2024 Aug; 664:124567. PMID: 39127173
Bacteria can evade antimicrobial therapy by hiding inside host cells such as macrophages. Here we examine the ability of PLGA nanoparticles to deliver antibiotics to intracellular bacteria, specifically focusing upon...
2.
Mitrovic A, Burden R, Softic A, Kavcic N
Front Pharmacol . 2024 Apr; 15:1394018. PMID: 38666021
No abstract available.
3.
Sereesongsaeng N, Burrows J, Scott C, Brix K, Burden R
Front Pharmacol . 2023 Nov; 14:1271435. PMID: 38026973
We previously identified that Cathepsin V (CTSV) expression is associated with poor prognosis in ER+ breast cancer, particularly within the Luminal A subtype. Examination of the molecular role of the...
4.
Ishaq F, Sereesongsaeng N, Johnston M, Scott C, Burden R
Chem Biol Interact . 2022 Mar; 356:109882. PMID: 35263611
Increasing use of nanomaterials in everyday products such as cosmetics, medicines and food packaging is of grave concern given the lack of understanding with regards the impact such materials have...
5.
Lin J, McCann A, Sereesongsaeng N, Burden J, Alsad A, Burden R, et al.
EMBO Rep . 2022 Jan; 23(4):e51932. PMID: 35080333
Expression of the deubiquitinase USP17 is induced by multiple stimuli, including cytokines (IL-4/6), chemokines (IL-8, SDF1), and growth factors (EGF), and several studies indicate it is required for cell proliferation...
6.
Sereesongsaeng N, McDowell S, Burrows J, Scott C, Burden R
Breast Cancer Res . 2020 Dec; 22(1):139. PMID: 33298139
Background: Lysosomal cysteine protease cathepsin V has previously been shown to exhibit elevated expression in breast cancer tissue and be associated with distant metastasis. Research has also identified that cathepsin...
7.
Al-Hashimi A, Venugopalan V, Rehders M, Sereesongsaeng N, Hein Z, Springer S, et al.
Int J Mol Sci . 2020 Dec; 21(23). PMID: 33266306
The significance of cysteine cathepsins for the liberation of thyroid hormones from the precursor thyroglobulin was previously shown by in vivo and in vitro studies. Cathepsin L is most important...
8.
Al-Hashimi A, Venugopalan V, Sereesongsaeng N, Tedelind S, Pinzaru A, Hein Z, et al.
Biochim Biophys Acta Mol Cell Res . 2020 Sep; 1867(12):118846. PMID: 32910988
Altered expression and/or localization of cysteine cathepsins is believed to involve in thyroid diseases including cancer. Here, we examined the localization of cathepsins B and V in human thyroid tissue...
9.
McDowell S, Gallaher S, Burden R, Scott C
Biochim Biophys Acta Mol Cell Res . 2020 Jun; 1867(10):118781. PMID: 32544418
Elevated expression of the cysteine protease Cathepsin S has been correlated with a number of different cancer types in recent years. As tools have been developed to enable more accurate...
10.
Wilkinson R, Burden R, McDowell S, McArt D, McQuaid S, Bingham V, et al.
J Oncol . 2019 Jul; 2019:3980273. PMID: 31346333
Cathepsin S (CTSS) has previously been implicated in a number of cancer types, where it is associated with poor clinical features and outcome. To date, patient outcome in breast cancer...