James F Burrows
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Explore the profile of James F Burrows including associated specialties, affiliations and a list of published articles.
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52
Citations
993
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Recent Articles
1.
Alsad A, Greene M, Tayyem M, Elmore B, Abed A, Burden R, et al.
Int J Pharm
. 2024 Aug;
664:124567.
PMID: 39127173
Bacteria can evade antimicrobial therapy by hiding inside host cells such as macrophages. Here we examine the ability of PLGA nanoparticles to deliver antibiotics to intracellular bacteria, specifically focusing upon...
2.
Wang Y, Shi D, Zou W, Jiang Y, Wang T, Chen X, et al.
Pharmaceutics
. 2024 May;
16(5).
PMID: 38794259
Peptides with antimicrobial activity or protease inhibitory activity are potential candidates to supplement traditional antibiotics or cancer chemotherapies. However, the potential of many peptides are limited by drawbacks such as...
3.
Sereesongsaeng N, Burrows J, Scott C, Brix K, Burden R
Front Pharmacol
. 2023 Nov;
14:1271435.
PMID: 38026973
We previously identified that Cathepsin V (CTSV) expression is associated with poor prognosis in ER+ breast cancer, particularly within the Luminal A subtype. Examination of the molecular role of the...
4.
Tracey S, Smyth P, Herron U, Burrows J, Porter A, Barelle C, et al.
RSC Adv
. 2023 Nov;
13(48):33721-33735.
PMID: 38020041
Intracellular delivery of proteins, peptides and biologics is an emerging field which has the potential to provide novel opportunities to target intracellular proteins, previously deemed 'undruggable'. However, the delivery of...
5.
Fei F, Wang T, Jiang Y, Chen X, Ma C, Zhou M, et al.
J Cell Mol Med
. 2023 May;
27(11):1565-1579.
PMID: 37210603
Staphylococcus aureus (S. aureus), one of the most prevalent bacteria found in atopic dermatitis lesions, can induce ongoing infections and inflammation by downregulating the expression of host defence peptides in...
6.
Liu S, Lin Y, Liu J, Chen X, Ma C, Xi X, et al.
Antibiotics (Basel)
. 2022 Aug;
11(8).
PMID: 36009917
Antimicrobial peptides (AMPs) are considered as promising antimicrobial agents due to their potent bioactivity. Palustrin-2 peptides were previously found to exhibit broad-spectrum antimicrobial activity with low haemolytic activity. Therefore, GL-29...
7.
Lin J, McCann A, Sereesongsaeng N, Burden J, Alsad A, Burden R, et al.
EMBO Rep
. 2022 Jan;
23(4):e51932.
PMID: 35080333
Expression of the deubiquitinase USP17 is induced by multiple stimuli, including cytokines (IL-4/6), chemokines (IL-8, SDF1), and growth factors (EGF), and several studies indicate it is required for cell proliferation...
8.
Stewart L, Gerner L, Rettel M, Stein F, Burrows J, Mills I, et al.
Cell Death Dis
. 2021 Nov;
12(11):1040.
PMID: 34725334
Calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) regulates cell and whole-body metabolism and supports tumorigenesis. The cellular impacts of perturbing CAMKK2 expression are, however, not yet fully characterised. By knocking down...
9.
Geddes L, Themistou E, Burrows J, Buchanan F, Carson L
Acta Biomater
. 2021 Jul;
134:261-275.
PMID: 34329786
Bioresorbable polymers composed of poly(D,L-lactide-co-glycolide) (PDLLGA) and poly(L-lactide-co-glycolide) (PLLGA) have become increasingly popular for the preparation of bone substitute constructs. However, there are reports of a delayed inflammatory reaction occurring...
10.
Jena L, Bennie L, McErlean E, Pentlavalli S, Glass K, Burrows J, et al.
J Nanobiotechnology
. 2021 May;
19(1):127.
PMID: 33947409
Glioblastoma multiforme (GBM) is an incurable aggressive brain cancer in which current treatment strategies have demonstrated limited survival benefit. In recent years, nitrogen-containing bisphosphonates (N-BPs) have demonstrated direct anticancer effects...