Robert J Bastidas
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Explore the profile of Robert J Bastidas including associated specialties, affiliations and a list of published articles.
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29
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1193
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Recent Articles
1.
Bastidas R, Kedzior M, Davidson R, Walsh S, Dolat L, Sixt B, et al.
Elife
. 2024 Feb;
12.
PMID: 38358795
Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen secretes Cdu1 (ChlaDUB1),...
2.
Bastidas R, Valdivia R
Curr Opin Microbiol
. 2023 May;
74:102330.
PMID: 37247566
Chlamydia trachomatis (Ct) is an intracellular bacterial pathogen that relies on the activity of secreted proteins known as effectors to promote replication and avoidance of immune clearance. Understanding the contribution...
3.
Bastidas R, Kedzior M, Davidson R, Walsh S, Dolat L, Sixt B, et al.
bioRxiv
. 2023 Mar;
PMID: 36909574
Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen secretes Cdu1 (ChlaDUB1),...
4.
Walsh S, Reitano J, Dickinson M, Kutsch M, Hernandez D, Barnes A, et al.
Cell Host Microbe
. 2022 Sep;
30(12):1671-1684.e9.
PMID: 36084633
Chlamydia trachomatis is the leading cause of sexually transmitted bacterial infections and a major threat to women's reproductive health in particular. This obligate intracellular pathogen resides and replicates within a...
5.
Kedzior M, Bastidas R
Methods Mol Biol
. 2019 Aug;
2042:185-204.
PMID: 31385277
Chlamydia is a major etiological agent of human disease that affects millions of individuals worldwide. Historically, our understanding of the mechanisms that contribute to its pathogenesis has been limited. However,...
6.
Panzetta M, Lujan A, Bastidas R, Damiani M, Valdivia R, Saka H
Front Microbiol
. 2019 Apr;
10:756.
PMID: 31024512
is the most common sexually transmitted bacterial pathogen in humans and a frequent cause of asymptomatic, persistent infections leading to serious complications, particularly in young women. displays a unique obligate...
7.
Pruneda J, Bastidas R, Bertsoulaki E, Swatek K, Santhanam B, Clague M, et al.
Nat Microbiol
. 2018 Nov;
3(12):1377-1384.
PMID: 30397340
Pathogenic bacteria are armed with potent effector proteins that subvert host signalling processes during infection. The activities of bacterial effectors and their associated roles within the host cell are often...
8.
Valdivia R, Bastidas R
J Bacteriol
. 2018 Oct;
200(24).
PMID: 30297356
has emerged as an important model system for the study of host pathogen interactions, in part due to a resurgence in the development of tools for its molecular genetic manipulation....
9.
Mojica S, Salin O, Bastidas R, Sunduru N, Hedenstrom M, Andersson C, et al.
Antimicrob Agents Chemother
. 2017 Aug;
61(10).
PMID: 28784680
The type II fatty acid synthesis (FASII) pathway is essential for bacterial lipid biosynthesis and continues to be a promising target for novel antibacterial compounds. Recently, it has been demonstrated...
10.
Sixt B, Bastidas R, Finethy R, Baxter R, Carpenter V, Kroemer G, et al.
Cell Host Microbe
. 2017 Jan;
21(1):113-121.
PMID: 28041929
Evading cell death is critical for Chlamydia to maintain a replicative niche, but the underlying mechanisms are unknown. We screened a library of Chlamydia mutants for modulators of cell death....