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Mateusz Kedzior

Explore the profile of Mateusz Kedzior including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 52
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Recent Articles
1.
Sajadi M, Abbasi A, Tehrani Z, Siska C, Clark R, Chi W, et al.
bioRxiv . 2024 Oct; PMID: 39464103
Anti-HIV envelope broadly neutralizing antibodies (bnAbs) are alternatives to conventional antiretrovirals with the potential to prevent and treat infection, reduce latent reservoirs, and/or mediate a functional cure. Clinical trials with...
2.
Khalek I, Senji Laxme R, Nguyen Y, Khochare S, Patel R, Woehl J, et al.
Sci Transl Med . 2024 Feb; 16(735):eadk1867. PMID: 38381847
Snakebite envenoming is a major global public health concern for which improved therapies are urgently needed. The antigenic diversity present in snake venom toxins from various species presents a considerable...
3.
Bastidas R, Kedzior M, Davidson R, Walsh S, Dolat L, Sixt B, et al.
Elife . 2024 Feb; 12. PMID: 38358795
Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen secretes Cdu1 (ChlaDUB1),...
4.
Bastidas R, Kedzior M, Davidson R, Walsh S, Dolat L, Sixt B, et al.
bioRxiv . 2023 Mar; PMID: 36909574
Many cellular processes are regulated by ubiquitin-mediated proteasomal degradation. Pathogens can regulate eukaryotic proteolysis through the delivery of proteins with de-ubiquitinating (DUB) activities. The obligate intracellular pathogen secretes Cdu1 (ChlaDUB1),...
5.
Garcia A, Kedzior M, Taton A, Li M, Young J, Kacar B
Geobiology . 2023 Jan; 21(3):390-403. PMID: 36602111
Carbon isotope biosignatures preserved in the Precambrian geologic record are primarily interpreted to reflect ancient cyanobacterial carbon fixation catalyzed by Form I RuBisCO enzymes. The average range of isotopic biosignatures...
6.
Kedzior M, Garcia A, Li M, Taton A, Adam Z, Young J, et al.
Cell Rep . 2022 Apr; 39(4):110726. PMID: 35476992
The earliest geochemical indicators of microbes-and the enzymes that powered them-extend back ∼3.8 Ga on Earth. Paleobiologists often attempt to understand these indicators by assuming that the behaviors of extant...
7.
Kedzior M, Kacar B
Bio Protoc . 2021 Nov; 11(20):e4199. PMID: 34761071
Phototrophic microorganisms are frequently engineered to regulate the expression and the activity of targeted enzymes of interest for specific biotechnological and agricultural applications. This protocol describes a method to evaluate...
8.
Kedzior M, Bastidas R
Methods Mol Biol . 2019 Aug; 2042:185-204. PMID: 31385277
Chlamydia is a major etiological agent of human disease that affects millions of individuals worldwide. Historically, our understanding of the mechanisms that contribute to its pathogenesis has been limited. However,...
9.
Kedzior M, Pawlak A, Seredynski R, Bania J, Platt-Samoraj A, Czemplik M, et al.
Microbiol Res . 2018 Feb; 207:211-225. PMID: 29458857
Cysteine proteases of the papain family, including mammalian cathepsins, play important physiological roles, however, their excessive activity may contribute to the development of various pathologies. Therefore, cysteine cathepsin inhibitors are...
10.
Seredynski R, Wolna D, Kedzior M, Gutowicz J
J Basic Microbiol . 2016 Jul; 57(1):34-40. PMID: 27406379
Protease secretion in Saccharomyces cerevisiae cultures is a complex process, important for the application of this organism in the food industry and biotechnology. Previous studies provide rather quantitative data, yielding...