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Robert A Coleman

Explore the profile of Robert A Coleman including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 901
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Recent Articles
1.
Kenworthy C, Haque N, Liou S, Chandris P, Wong V, Dziuba P, et al.
Biophys J . 2022 Apr; 121(9):1738-1752. PMID: 35364106
Chromatin remodelers actively target arrays of acetylated nucleosomes at select enhancers and promoters to facilitate or shut down the repeated recruitment of RNA polymerase II during transcriptional bursting. It is...
2.
Rigano A, Ehmsen S, Ozturk S, Ryan J, Balashov A, Hammer M, et al.
Nat Methods . 2021 Dec; 19(2):256. PMID: 34952955
No abstract available.
3.
Rigano A, Ehmsen S, Ozturk S, Ryan J, Balashov A, Hammer M, et al.
Nat Methods . 2021 Dec; 18(12):1489-1495. PMID: 34862503
For quality, interpretation, reproducibility and sharing value, microscopy images should be accompanied by detailed descriptions of the conditions that were used to produce them. Micro-Meta App is an intuitive, highly...
4.
Coleman R, Fulford M
Food Ethics . 2021 Nov; 7(1):1. PMID: 34722856
Despite worldwide attention given to food access, very little progress has been made under the current model. Recognizing that individual engagement is likely based on individual experiences and perceptions, this...
5.
Desai R, Chen X, Martin B, Chaturvedi S, Hwang D, Li W, et al.
Science . 2021 Jul; 373(6557). PMID: 34301855
Stochastic fluctuations in gene expression ("noise") are often considered detrimental, but fluctuations can also be exploited for benefit (e.g., dither). We show here that DNA base excision repair amplifies transcriptional...
6.
Biswas J, Li W, Singer R, Coleman R
Cold Spring Harb Perspect Biol . 2021 Jun; 13(12). PMID: 34127450
Within the nucleus, messenger RNA is generated and processed in a highly organized and regulated manner. Messenger RNA processing begins during transcription initiation and continues until the RNA is translated...
7.
Liou S, Singh S, Singer R, Coleman R, Liu W
Commun Biol . 2021 Mar; 4(1):397. PMID: 33767390
The tumor suppressor p53 protein activates expression of a vast gene network in response to stress stimuli for cellular integrity. The molecular mechanism underlying how p53 targets RNA polymerase II...
8.
Park S, Hauver J, Zhang Y, Revyakin A, Coleman R, Tjian R, et al.
Structure . 2020 Aug; 28(12):1337-1343.e4. PMID: 32763141
Single-molecule detection and manipulation is a powerful tool for unraveling dynamic biological processes. Unfortunately, success in such experiments is often challenged by tethering the biomolecule(s) of interest to a biocompatible...
9.
Woodward D, Coleman R, Woodrooffe A, Spada C, Wang J
J Ocul Pharmacol Ther . 2020 Jul; 36(8):636-648. PMID: 32640926
JV-GL1 is an efficacious, potent, and long-acting antiglaucoma agent, according to studies in ocular normotensive and hypertensive monkeys. As an obligatory step in the drug development process, studies with exaggerated...
10.
Drosopoulos W, Vierra D, Kenworthy C, Coleman R, Schildkraut C
Cell Rep . 2020 Feb; 30(5):1329-1341.e5. PMID: 32023453
Human DNA polymerase delta (Pol δ) forms a holoenzyme complex with the DNA sliding clamp proliferating cell nuclear antigen (PCNA) to perform its essential roles in genome replication. Here, we...