Jogeshwar Mukherjee
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Explore the profile of Jogeshwar Mukherjee including associated specialties, affiliations and a list of published articles.
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99
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1688
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Recent Articles
1.
Paclibar C, Schafer D, Biju A, Karim F, Sison S, Liang C, et al.
Molecules
. 2025 Mar;
30(5).
PMID: 40076215
Dual specificity tyrosine-phosphorylation regulated kinase 1A (DYRK1A), a phosphorylation kinase, is localized within the central nervous system and is linked to hyperphosphorylation of Tau. Imaging of DYRK1A may provide an...
2.
Liang C, Okamoto A, Karim F, Kawauchi S, Melkonyan L, Danh T, et al.
Neuroimage
. 2025 Feb;
309:121092.
PMID: 39978704
The 3xTg-AD transgenic mouse model develops Aβ plaque and tau pathology and is purported to closely resemble pathological development in the human Alzheimer's disease (AD) brain. Nicotinic acetylcholine receptors (nAChRs)...
3.
Sison S, Paclibar C, Liang C, Mukherjee J
Molecules
. 2024 Jul;
29(14).
PMID: 39064887
Using a molecular modeling approach for Tau-binding sites, we modified our previously reported imaging agent, [I]INFT, for the potential improvement of binding properties to Tau in an Alzheimer's disease (AD)...
4.
Sandhu Y, Bath H, Shergill J, Liang C, Syed A, Ngo A, et al.
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39063132
The diagnostic value of imaging Aβ plaques in Alzheimer's disease (AD) has accelerated the development of fluorine-18 labeled radiotracers with a longer half-life for easier translation to clinical use. We...
5.
Liang C, Paclibar C, Gonzaga N, Sison S, Bath H, Biju A, et al.
Neurol Int
. 2024 Apr;
16(2):419-431.
PMID: 38668128
Therapeutic antibodies for reducing Aβ plaque load in Alzheimer's disease (AD) is currently making rapid progress. The diagnostic imaging of Aβ plaque load in AD has been underway and is...
6.
Shah N, Ghazaryan N, Gonzaga N, Paclibar C, Biju A, Liang C, et al.
Molecules
. 2024 Jan;
29(1).
PMID: 38202606
In an effort to further understand the challenges facing in vivo imaging probe development for the N-methyl-D-aspartate (NMDA) receptor ion channel, we have evaluated the effect of glutamate on the...
7.
Singh K, Ngo A, Keerthisinghe O, Patel K, Liang C, Mukherjee J
Molecules
. 2023 Dec;
28(24).
PMID: 38138615
Nicotinic acetylcholine receptors (nAChRs) are involved in various central nervous system functions and have also been implicated in several neurodegenerative disorders. The heteromeric α4β2* and homomeric α7 are two major...
8.
Zammit M, Kao C, Zhang H, Tsai H, Holderman N, Mitchell S, et al.
Int J Mol Sci
. 2023 Nov;
24(21).
PMID: 37958495
Positron emission tomography (PET) radioligands that bind with high-affinity to α4β2-type nicotinic receptors (α4β2Rs) allow for in vivo investigations of the mechanisms underlying nicotine addiction and smoking cessation. Here, we...
9.
Bhuiyan M, Souris J, Kucharski A, Freifelder R, Mukherjee J, Chen C
J Labelled Comp Radiopharm
. 2023 Nov;
67(1):31-36.
PMID: 37927198
The α4β2 nicotinic acetylcholine receptor (nAChR) ligand 2-[ F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine ([ F]nifene) has been synthesized in 10% decay-corrected radiochemical yield using the IBA Synthera® platform (IBA Cyclotron Solutions, Louvain-la-Neuve, Belgium) with...
10.
Limpengco R, Liang C, Sandhu Y, Mukherjee J
Molecules
. 2023 Aug;
28(15).
PMID: 37570739
Aggregation of Tau protein into paired helical filaments causing neurofibrillary tangles (NFT) is a neuropathological feature in Alzheimer's disease (AD). This study aimed to develop and evaluate the effectiveness of...