Richard J Davis
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Explore the profile of Richard J Davis including associated specialties, affiliations and a list of published articles.
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42
Citations
926
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Recent Articles
1.
Jarvis D, Pope E, Duteil M, Furtbauer I, Brown M, Davis R, et al.
J Fish Biol
. 2022 Jul;
101(5):1361-1365.
PMID: 35906859
The authors investigated left-right turning preferences of n = 260 juvenile European sea bass (Dicentrarchus labrax) reared in ambient conditions and ocean acidification (OA) conditions or in ambient conditions but...
2.
Zhao C, Boles N, Miller J, Kawola S, Temple S, Davis R, et al.
J Vis Exp
. 2017 Aug;
(126).
PMID: 28829422
Degenerative retinal diseases such as age-related macular degeneration (AMD) are the leading cause of irreversible vision loss worldwide. AMD is characterized by the degeneration of retinal pigment epithelial (RPE) cells,...
3.
Davis R, Alam N, Zhao C, Muller C, Saini J, Blenkinsop T, et al.
Stem Cell Reports
. 2017 Jun;
9(1):42-49.
PMID: 28625537
Age-related macular degeneration (AMD) is a common cause of central visual loss in the elderly. Retinal pigment epithelial (RPE) cell loss occurs early in the course of AMD and RPE...
4.
Davis R, Blenkinsop T, Campbell M, Borden S, Charniga C, Lederman P, et al.
J Ocul Pharmacol Ther
. 2016 May;
32(5):304-9.
PMID: 27182605
Purpose: Numerous preclinical studies have shown that transplantation of stem cell-derived retinal pigment epithelial cell (RPE) preserves photoreceptor cell anatomy in the dystrophic Royal College of Surgeons (RCS) rat. How...
5.
Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, et al.
Cancer Res
. 2015 Mar;
75(10):1992-2004.
PMID: 25769723
Prostate cancer is the second leading form of cancer-related death in men. In a subset of prostate cancer patients, increased chemokine signaling IL8 and IL6 correlates with castrate-resistant prostate cancer...
6.
Tsang S, Chan L, Tsai Y, Wu W, Hsu C, Yang J, et al.
Trans Am Ophthalmol Soc
. 2015 Feb;
112:103-15.
PMID: 25646031
Purpose: To assess the functional consequences of silencing of tuberin, an inhibitor of the mTOR signaling pathway, in a preclinical model of retinitis pigmentosa (RP) in order to test the...
7.
Sutton J, Clark D, Higgs C, de Groot M, Harris N, Taylor A, et al.
Bioorg Med Chem Lett
. 2014 Apr;
24(9):2212-21.
PMID: 24703233
In this Letter, we present the results of a hit-finding and lead optimization programme against the EP4 receptor (EP4R). In a short time period, we were able to discover five...
8.
Yang J, Li Y, Erol D, Wu W, Tsai Y, Li X, et al.
Graefes Arch Clin Exp Ophthalmol
. 2014 Feb;
252(3):423-31.
PMID: 24492934
Purpose: The objective of this study was to determine whether cells from the conjunctiva could be reprogrammed into induced pluripotent stem (iPS) cells, providing an alternative source of stem cells....
9.
Davis R, Hsu C, Tsai Y, Wert K, Sancho-Pelluz J, Lin C, et al.
J Neurosci
. 2013 Aug;
33(33):13475-83.
PMID: 23946405
The third-most common cause of autosomal recessive retinitis pigmentosa (RP) is due to defective cGMP phosphodiesterase-6 (PDE6). Previous work using viral gene therapy on PDE6-mutant mouse models demonstrated photoreceptors can...
10.
Wert K, Skeie J, Davis R, Tsang S, Mahajan V
J Vis Exp
. 2012 Dec;
(69).
PMID: 23207897
The loss of sight affects approximately 3.4 million people in the United States and is expected to increase in the upcoming years.(1) Recently, gene therapy and stem cell transplantations have...