Razvan Nutiu
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Explore the profile of Razvan Nutiu including associated specialties, affiliations and a list of published articles.
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24
Citations
884
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Recent Articles
1.
Rice G, Shivashankar V, Ma E, Baryza J, Nutiu R
Mol Cell
. 2020 Nov;
80(5):892-902.e4.
PMID: 33188727
Primary microRNAs (miRNAs) are the precursors of miRNAs that modulate the expression of most mRNAs in humans. They fold up into a hairpin structure that is cleaved at its base...
2.
Rice G, Nutiu R, Gampe C
Methods Mol Biol
. 2018 Dec;
1870:81-87.
PMID: 30539548
Introduction of chemical labels into biomolecules is of utmost importance in chemical biology research. However, methods for selective chemical labeling of in vitro transcribed RNA are scarce. Herein, we describe...
3.
Tuck A, Natarajan K, Rice G, Borawski J, Mohn F, Rankova A, et al.
Life Sci Alliance
. 2018 Nov;
1(4):e201800124.
PMID: 30456373
Eukaryotic genomes produce RNAs lacking protein-coding potential, with enigmatic roles. We integrated three approaches to study large intervening noncoding RNA (lincRNA) gene functions. First, we profiled mouse embryonic stem cells...
4.
Mustoe A, Busan S, Rice G, Hajdin C, Peterson B, Ruda V, et al.
Cell
. 2018 Mar;
173(1):181-195.e18.
PMID: 29551268
mRNAs can fold into complex structures that regulate gene expression. Resolving such structures de novo has remained challenging and has limited our understanding of the prevalence and functions of mRNA...
5.
Smith T, Pheng Lim S, Yue K, Busby S, Arora R, Seh C, et al.
J Biomol Screen
. 2014 Sep;
20(1):153-63.
PMID: 25252731
Dengue virus (DENV) is the most significant mosquito-borne viral pathogen in the world and is the cause of dengue fever. The DENV RNA-dependent RNA polymerase (RdRp) is conserved among the...
6.
Li J, Kim T, Nutiu R, Ray D, Hughes T, Zhang Z
Genome Res
. 2014 Mar;
24(5):775-85.
PMID: 24663241
It is commonly known that mammalian microRNAs (miRNAs) guide the RNA-induced silencing complex (RISC) to target mRNAs through the seed-pairing rule. However, recent experiments that coimmunoprecipitate the Argonaute proteins (AGOs),...
7.
Han H, Nutiu R, Moffat J, Blencowe B
Cell
. 2011 Sep;
146(6):1044, 1044.e1-2.
PMID: 21925324
No abstract available.
8.
Nutiu R, Friedman R, Luo S, Khrebtukova I, Silva D, Li R, et al.
Nat Biotechnol
. 2011 Jun;
29(7):659-64.
PMID: 21706015
Several methods for characterizing DNA-protein interactions are available, but none have demonstrated both high throughput and quantitative measurement of affinity. Here we describe 'high-throughput sequencing'-'fluorescent ligand interaction profiling' (HiTS-FLIP), a...
9.
Xiao X, Wang Z, Jang M, Nutiu R, Wang E, Burge C
Nat Struct Mol Biol
. 2009 Sep;
16(10):1094-100.
PMID: 19749754
Pre-mRNA splicing is regulated through the combinatorial activity of RNA motifs, including splice sites and splicing regulatory elements. Here we show that the activity of the G-run (polyguanine sequence) class...
10.
Nakamura I, Shi A, Nutiu R, Yu J, Li Y
Phys Rev E Stat Nonlin Soft Matter Phys
. 2009 Apr;
79(3 Pt 1):031906.
PMID: 19391970
DNA aptamers are molecular biosensors consisting of single functionalized DNA molecules, which can bind to specific targets or complementary DNA sequences. The binding kinetics of DNA aptamers is studied by...