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Life Science Alliance

Life Science Alliance is a scientific journal, published since 2017 in English. The journal's country of origin is United States and its primary focus areas are biochemistry, biology, cell biology and molecular biology.

Details
Abbr. Life Sci Alliance
Start 2017
End Continuing
Frequency Monthly
e-ISSN 2575-1077
Country United States
Language English
Metrics
h-index / Ranks: 9184 37
SJR / Ranks: 1282 1907
CiteScore / Ranks: 2894 7.00
JIF / Ranks: 1945 4.4
Recent Articles
1.
Jocher G, Ozcelik G, Muller S, Hsia H, Lastra Osua M, Hofmann L, et al.
Life Sci Alliance . 2025 Mar; 8(5). PMID: 40081988
The cell surface receptor TREM2 is a key genetic risk factor and drug target in Alzheimer's disease (AD). In the brain, TREM2 is expressed in microglia, where it undergoes proteolytic...
2.
Mohammad I, Giannotti M, Fourgous E, Boublik Y, Fernandez A, Le Roux A, et al.
Life Sci Alliance . 2025 Mar; 8(5). PMID: 40081987
Src tyrosine kinase regulates cell growth and adhesion through membrane signaling, and its deregulation is associated with cancer. Although active Src is anchored to the plasma membrane, the role of...
3.
Cao-Garcia F, Walker J, Board S, Alonso-Caballero A
Life Sci Alliance . 2025 Mar; 8(5). PMID: 40054876
Surface sensing initiates bacterial colonization of substrates. The protein PilY1 plays key roles during this process-surface detection, host adhesion, and motility-while experiencing mechanical perturbations of varying magnitudes. In , the...
4.
Torres Esteban M, Stewart M, Bragginton E, Meroni A, Pellizzari A, Jeanrenaud A, et al.
Life Sci Alliance . 2025 Mar; 8(5). PMID: 40049731
Ubiquitylation is critically implicated in the recognition and repair of DNA double-strand breaks. The adaptor protein MDC1 mediates the recruitment of the key DNA damage responsive E3 ubiquitin ligase RNF8...
5.
Chen Y, Reddy S, Suzuki A
Life Sci Alliance . 2025 Mar; 8(5). PMID: 40037894
The cell cycle is a crucial process for cell proliferation, differentiation, and development. Numerous genes and proteins play pivotal roles at specific cell cycle stages to ensure precise regulation of...
6.
Ambite I, Chao S, Rosenblad T, Hopkins R, Storm P, Ng Y, et al.
Life Sci Alliance . 2025 Mar; 8(3). PMID: 40036168
This study investigated the molecular basis of disease severity in acute pyelonephritis (APN), a common and potentially life-threatening bacterial infection. Two cohorts of infants with febrile urinary tract infection were...
7.
Roman-Trufero M, Kleijn I, Blighe K, Zhou J, Saavedra-Garcia P, Gaffar A, et al.
Life Sci Alliance . 2025 Mar; 8(5). PMID: 40032489
The integrated stress response (ISR) is a corrective physiological programme to restore cellular homeostasis that is based on the attenuation of global protein synthesis and a resource-enhancing transcriptional programme. GCN2...
8.
Furrer R, Dilbaz S, Steurer S, Santos G, Karrer-Cardel B, Ritz D, et al.
Life Sci Alliance . 2025 Feb; 8(5). PMID: 40021220
Dysferlin is a transmembrane protein that plays a prominent role in membrane repair of damaged muscle fibers. Accordingly, mutations in the dysferlin gene cause progressive muscular dystrophies, collectively referred to...
9.
Kirwan K, Puerta-Alvarado V, Waites C
Life Sci Alliance . 2025 Feb; 8(5). PMID: 40021219
CHMP2b is a core component of the ESCRT pathway that catalyzes formation of multivesicular bodies for endolysosomal protein degradation. Although mutation/loss-of-function of CHMP2b promotes presynaptic dysfunction and degeneration, indicating its...
10.
Miller C, Golovina E, Gokuladhas S, Wicker J, Jacobsen J, OSullivan J
Life Sci Alliance . 2025 Feb; 8(5). PMID: 40000109
Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous neurodevelopmental condition with a high prevalence of co-occurring conditions, contributing to increased difficulty in long-term management. Genome-wide association studies have identified variants shared between...