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Ravinder Raju

Explore the profile of Ravinder Raju including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 115
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Recent Articles
1.
OKonek J, Illarionov P, Stewart Khursigara D, Ambrosino E, Izhak L, Castillo 2nd B, et al.
J Clin Invest . 2011 Jan; 121(2):683-94. PMID: 21245578
Type 1 or invariant NKT (iNKT) cell agonists, epitomized by α-galactosylceramide, protect against cancer largely by IFN-γ-dependent mechanisms. Here we describe what we believe to be a novel IFN-γ-independent mechanism...
2.
Raju R, Castillo B, Richardson S, Thakur M, Severins R, Kronenberg M, et al.
Bioorg Med Chem Lett . 2009 Jun; 19(15):4122-5. PMID: 19535248
Four 3''- and 4''-deoxy and -fluorogalactosyl ceramides were synthesized, and their ability to stimulate iNKT cells, based on levels of IL-2 production, was assessed in three NKT cell receptor hybridomas....
3.
Velmourougane G, Raju R, Bricard G, Im J, Besra G, Porcelli S, et al.
Bioorg Med Chem Lett . 2009 Jun; 19(13):3386-8. PMID: 19481452
An alpha-galactosyl ceramide (alpha-GalCer) 2 was synthesized and evaluated for its ability to stimulate iNKT-cell proliferation and elicit T-helper cytokines, IL-4 and IFNgamma. Compound 2 combines the acyl chain of...
4.
Albaneze-Walker J, Raju R, Vance J, Goodman A, Reeder M, Liao J, et al.
Org Lett . 2009 Mar; 11(7):1463-6. PMID: 19281220
Aryl imidazolylsulfonates participate as electrophilic coupling partners in palladium-mediated cross-coupling reactions. The aryl imidazolylsulfonates display good stability while maintaining good reactivity in a variety of palladium-catalyzed coupling reactions. Imidazolylsulfonates are...
5.
Kinjo Y, Pei B, Bufali S, Raju R, Richardson S, Imamura M, et al.
Chem Biol . 2008 Jul; 15(7):654-64. PMID: 18635002
Mouse natural killer T (NKT) cells expressing an invariant T cell antigen receptor (TCR) recognize glycosphingolipids (GSLs) from Sphingomonas bacteria. The synthetic antigens previously tested, however, were designed to closely...
6.
Busacca C, Raju R, Grinberg N, Haddad N, James-Jones P, Lee H, et al.
J Org Chem . 2008 Jan; 73(4):1524-31. PMID: 18197688
The reduction of tertiary phosphine oxides (TPOs) and sulfides with diisobutylaluminum hydride (DIBAL-H) has been studied in detail. An extensive solvent screen has revealed that hindered aliphatic ethers, such as...
7.
Raju R, Allen L, Le T, Taylor C, Howell A
Org Lett . 2007 Apr; 9(9):1699-701. PMID: 17407303
[reaction: see text] The cross metathesis reactivities of alpha-methylene-gamma-butyrolactone and an alpha-methylene-delta-lactone have been investigated. alpha-Methylene-gamma-butyrolactone undergoes rapid and efficient olefin isomerization in the presence of second-generation metathesis catalysts. However,...
8.
Raju R, Howell A
Org Lett . 2006 May; 8(10):2139-41. PMID: 16671801
[reaction: see text] 3-Alkylideneoxetan-2-ones have been prepared in good to excellent yields with high Z-selectivity by olefin cross metathesis with 3-methyleneoxetan-2-ones in the presence of second generation metathesis catalysts 1...