Rajesh Chandramohanadas
Overview
Explore the profile of Rajesh Chandramohanadas including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
573
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0
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Recent Articles
1.
Prasad R, Kadam A, Padippurackal V, Pulikuttymadom Balasubramanian A, Kumar Chandrakumaran N, Suresh Rangari K, et al.
J Biomol Struct Dyn
. 2024 Mar;
:1-15.
PMID: 38520147
Spike glycoprotein has a significant role in the entry of SARS-CoV-2 to host cells, which makes it a potential drug target. Continued accumulation of non-synonymous mutations in the receptor binding...
2.
Reghunandanan K, T P A, Krishnan N, K M D, Prasad R, Nelson-Sathi S, et al.
J Biomol Struct Dyn
. 2023 Jul;
42(12):6200-6211.
PMID: 37424150
Owing to its life cycle involving multiple hosts and species-specific biological complexities, a vaccine against , the causative agent of remains elusive. This makes chemotherapy the only viable means to...
3.
Banas A, Banas K, Chu T, Naidu R, Hutchinson P, Agrawal R, et al.
Commun Chem
. 2023 Jan;
4(1):129.
PMID: 36697584
Malaria, caused by parasites of the species Plasmodium, is among the major life-threatening diseases to afflict humanity. The infectious cycle of Plasmodium is very complex involving distinct life stages and...
4.
Ong J, Oh J, Yong Ang X, Naidu R, Chu T, Im J, et al.
Spectrochim Acta A Mol Biomol Spectrosc
. 2022 Nov;
286:122026.
PMID: 36395614
Malaria is a life-threatening infectious disease caused by parasites of the genus Plasmodium. Understanding the biological features of various parasite forms is important for the optical diagnosis and defining pathological...
5.
Chia W, Gomez-Lorenzo M, Castellote I, Tong J, Chandramohanadas R, Thu Chu T, et al.
ACS Chem Biol
. 2021 Oct;
16(11):2348-2372.
PMID: 34609851
The search for new antimalarial drugs with unexplored mechanisms of action is currently one of the main objectives to combat the resistance already in the clinic. New drugs should target...
6.
Malleret B, El Sahili A, Tay M, Carissimo G, Ong A, Novera W, et al.
Nat Microbiol
. 2021 Jul;
6(8):991-999.
PMID: 34294905
More than one-third of the world's population is exposed to Plasmodium vivax malaria, mainly in Asia. P. vivax preferentially invades reticulocytes (immature red blood cells). Previous work has identified 11...
7.
Loh D, Yong W, Yapeter J, Subburaj K, Chandramohanadas R
Comput Med Imaging Graph
. 2021 Feb;
88:101845.
PMID: 33582593
Accurate and early diagnosis is critical to proper malaria treatment and hence death prevention. Several computer vision technologies have emerged in recent years as alternatives to traditional microscopy and rapid...
8.
Indari O, Chandramohanadas R, Jha H
Pathog Dis
. 2020 Dec;
79(1).
PMID: 33355336
Plasmodium falciparum infection-mediated Epstein-Barr virus (EBV) reactivation is well established in malaria-endemic countries. We hypothesize that, during malaria onset, the reactivated EBV can infect human brain microvascular endothelial cells (HBECs)....
9.
Tayebi M, Zhou Y, Tripathi P, Chandramohanadas R, Ai Y
Anal Chem
. 2020 Jul;
92(15):10733-10742.
PMID: 32613828
Exosomes are nanosized (30-150 nm) extracellular vesicles (EVs) secreted by various cell types. They are easily accessible in biological fluids and contain specific disease biomarkers, making them attractive for diagnosis...
10.
Patra A, Hingamire T, Belekar M, Xiong A, Subramanian G, Bozdech Z, et al.
Antimicrob Agents Chemother
. 2020 Feb;
64(5).
PMID: 32071059
We report a systematic, cellular phenotype-based antimalarial screening of the Medicines for Malaria Venture Pathogen Box collection, which facilitated the identification of specific blockers of late-stage intraerythrocytic development of First,...