R C LeBoeuf
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Explore the profile of R C LeBoeuf including associated specialties, affiliations and a list of published articles.
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51
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1121
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Recent Articles
1.
Rider T, LeBoeuf R, Tso P, Jandacek R
Lipids
. 2016 Mar;
51(4):497-504.
PMID: 26949102
The ready availability and ease of use of kits for the measurement of serum lipids has greatly facilitated these measurements. In many cases it would be convenient to use these...
2.
Wei H, Averill M, McMillen T, Dastvan F, Mitra P, Subramanian S, et al.
Nutr Diabetes
. 2014 Feb;
4:e108.
PMID: 24567123
Background: Obesity is associated with reduced levels of circulating high-density lipoproteins (HDLs) and its major protein, apolipoprotein (apo) A-I. As a result of the role of HDL and apoA-I in...
3.
McMillen T, Minami E, LeBoeuf R
Nutr Diabetes
. 2013 Jun;
3:e79.
PMID: 23797386
Background: Obesity has become an epidemic in many countries and is supporting a billion dollar industry involved in promoting weight loss through diet, exercise and surgical procedures. Because of difficulties...
4.
LeBoeuf R, Schreyer S
Trends Cardiovasc Med
. 2011 Jan;
8(3):131-8.
PMID: 21235923
Tumor necrosis factor (TNF-α)-α is a cytokine exhibiting a plethora of activities involved in inflammation, immune regulation, and energy metabolism. TNF is produced by many cell types, including cells found...
5.
Vidal J, Verchere C, Andrikopoulos S, Wang F, Hull R, Cnop M, et al.
Diabetologia
. 2003 Mar;
46(1):71-9.
PMID: 12637985
Aims/hypothesis: Islet amyloid deposits are present in over 85% of Type 2 diabetic patients and have been suggested to be pathogenic. The mechanism that converts islet amyloid polypeptide (IAPP), the...
6.
Schreyer S, Cummings D, McKnight G, LeBoeuf R
Diabetes
. 2001 Oct;
50(11):2555-62.
PMID: 11679434
The mechanisms by which obesity contributes to diabetic phenotypes remain unclear. We evaluated the role of protein kinase A (PKA) signaling events in mediating diabetes associated with obesity. PKA comprises...
7.
Kirk E, Heinecke J, LeBoeuf R
J Clin Invest
. 2001 Jun;
107(12):1545-53.
PMID: 11413162
It has been proposed that elevated levels of tissue iron increase the risk for atherosclerosis, perhaps by favoring the formation of pro-atherogenic oxidized LDL. Working with apoE-deficient (apoE(-/-)) mice, which...
8.
Deeg M, Bowen R, Williams M, Olson L, Kirk E, LeBoeuf R
Am J Physiol Endocrinol Metab
. 2001 Jun;
281(1):E147-54.
PMID: 11404232
Glycosylphosphatidylinositol-specific phospholipase D (GPI-PLD) is a high-density lipoprotein-associated protein. However, the tissue source(s) for circulating GPI-PLD and whether serum levels are regulated are unknown. Because the diabetic state alters lipoprotein...
9.
Validation of whole-body magnetic resonance spectroscopy as a tool to assess murine body composition
Mystkowski P, Shankland E, Schreyer S, LeBoeuf R, Schwartz R, Cummings D, et al.
Int J Obes Relat Metab Disord
. 2000 Jul;
24(6):719-24.
PMID: 10878678
Objective: To evaluate proton magnetic resonance spectroscopy (MRS) as a tool for the non-invasive assessment of murine body composition. Design: Twenty C57/BL6 male mice with a wide range of body...
10.
Kirk E, Dinauer M, Rosen H, Chait A, Heinecke J, LeBoeuf R
Arterioscler Thromb Vasc Biol
. 2000 Jun;
20(6):1529-35.
PMID: 10845868
Superoxide, the reduced form of molecular oxygen, has been implicated in the genesis of vascular disease. One potential mechanism involves oxidation of low density lipoprotein into an atherogenic particle. A...