R C LeBoeuf
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Explore the profile of R C LeBoeuf including associated specialties, affiliations and a list of published articles.
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51
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1121
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Recent Articles
11.
Clee S, Bissada N, Miao F, Miao L, Marais A, Henderson H, et al.
J Lipid Res
. 2000 Apr;
41(4):521-31.
PMID: 10744772
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein metabolism, and has been hypothesized to exert either pro- or anti-atherogenic effects, depending on its localization. Decreased plasma LPL activity is...
12.
HARTE R, Kirk E, Rosenfeld M, LeBoeuf R
Horm Metab Res
. 1999 Dec;
31(10):570-5.
PMID: 10596967
C57BL/6 female mice were fed high fat diets containing different types of carbohydrate (sucrose or corn starch) and contents of cholesterol (0.03 % or 1 %) to identify early metabolic...
13.
Eldar-Finkelman H, Schreyer S, Shinohara M, LeBoeuf R, KREBS E
Diabetes
. 1999 Jul;
48(8):1662-6.
PMID: 10426388
Although the precise mechanisms contributing to insulin resistance and type 2 diabetes are unknown, it is believed that defects in downstream components of the insulin signaling pathway may be involved....
14.
Knopp E, Arndt T, Eng K, Caldwell M, LeBoeuf R, Deeb S, et al.
Mamm Genome
. 1999 May;
10(6):601-5.
PMID: 10341094
Phospholipid hydroperoxide glutathione peroxidase (PHGPx), also known as glutathione peroxidase 4 (GPX4), is a 19-kDa, monomeric enzyme that protects cells from lipid peroxide-mediated damage by catalyzing the reduction of lipid...
15.
Dietary antioxidants inhibit development of fatty streak lesions in the LDL receptor-deficient mouse
Crawford R, Kirk E, Rosenfeld M, LeBoeuf R, Chait A
Arterioscler Thromb Vasc Biol
. 1998 Sep;
18(9):1506-13.
PMID: 9743241
Oxidized low density lipoprotein (LDL) promotes atherogenesis. Although pharmacological antioxidants such as probucol inhibit both LDL oxidation and atherosclerosis in hyperlipidemic animals, the effects of natural antioxidants such as vitamin...
16.
LeBoeuf R, Caldwell M, Guo Y, Metz C, Davitz M, Olson L, et al.
Mamm Genome
. 1998 Aug;
9(9):710-4.
PMID: 9716655
Glycosylphosphatidylinositol-specific phospholipase D (GPI-PLD) is an 110-kDa monomeric protein found in the circulation that is capable of degrading the GPI anchor utilized by dozens of cell-surface proteins in the presence...
17.
Schreyer S, Chua Jr S, LeBoeuf R
J Clin Invest
. 1998 Jul;
102(2):402-11.
PMID: 9664082
TNF-alpha may play a role in mediating insulin resistance associated with obesity. This concept is based on studies of obese rodents and humans, and cell culture models. TNF elicits cellular...
18.
Kirk E, Sutherland P, Wang S, Chait A, LeBoeuf R
J Nutr
. 1998 Jun;
128(6):954-9.
PMID: 9614153
Susceptibility to atherosclerosis is determined by a combination of genetic and environmental factors, including diet. Consumption of diets rich in soy protein has been claimed to protect against the development...
19.
Schreyer S, Wilson D, LeBoeuf R
Atherosclerosis
. 1998 Apr;
136(1):17-24.
PMID: 9544727
Non-insulin-dependent diabetes mellitus (NIDDM) is a major risk factor for the development of atherosclerosis in humans. The development of an animal model that displays accelerated atherosclerosis associated with NIDDM will...
20.
Chiu D, Oram J, LeBoeuf R, Alpers C, OBrien K
Arterioscler Thromb Vasc Biol
. 1997 Dec;
17(11):2350-8.
PMID: 9409201
Accumulation of cholesteryl esters within cells of the arterial intima is a hallmark of atherosclerosis. A small number of proteins have been shown in vitro to be upregulated by cellular...