Purna Mukherjee
Overview
Explore the profile of Purna Mukherjee including associated specialties, affiliations and a list of published articles.
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36
Citations
1330
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Recent Articles
1.
Duraj T, Kalamian M, Zuccoli G, Maroon J, DAgostino D, Scheck A, et al.
BMC Med
. 2024 Dec;
22(1):578.
PMID: 39639257
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally lethal prognosis despite maximal standard therapies. Here, we present a consensus treatment protocol based on the...
2.
Lee D, Ta L, Mukherjee P, Duraj T, Domin M, Greenwood B, et al.
ASN Neuro
. 2024 Dec;
16(1):2422268.
PMID: 39621724
Energy is necessary for tumor cell viability and growth. Aerobic glucose-driven lactic acid fermentation is a common metabolic phenotype seen in most cancers including malignant gliomas. This metabolic phenotype is...
3.
Seyfried T, Mukherjee P, Lee D, Ta L, Nations L
Front Nutr
. 2023 Apr;
10:1157517.
PMID: 37057065
Background: Mast cell tumors (MCT) are common neoplasms in dogs and are similar to most other malignant cancers in requiring glucose for growth, regardless of histological grade. Ketogenic metabolic therapy...
4.
Seyfried T, Arismendi-Morillo G, Zuccoli G, Lee D, Duraj T, Elsakka A, et al.
Front Oncol
. 2022 Sep;
12:968351.
PMID: 36059707
Glioblastoma (GBM), similar to most cancers, is dependent on fermentation metabolism for the synthesis of biomass and energy (ATP) regardless of the cellular or genetic heterogeneity seen within the tumor....
5.
Gabriele V, Mazhabi R, Alexander N, Mukherjee P, Seyfried T, Nwaji N, et al.
Pharmaceutics
. 2021 Jul;
13(7).
PMID: 34206894
Melanin nanoparticles are known to be biologically benign to human cells for a wide range of concentrations in a high glucose culture nutrition. Here, we show cytotoxic behavior at high...
6.
Seyfried T, Shivane A, Kalamian M, Maroon J, Mukherjee P, Zuccoli G
Front Nutr
. 2021 Jun;
8:682243.
PMID: 34136522
Successful treatment of glioblastoma (GBM) remains futile despite decades of intense research. GBM is similar to most other malignant cancers in requiring glucose and glutamine for growth, regardless of histological...
7.
Seyfried T, Arismendi-Morillo G, Mukherjee P, Chinopoulos C
iScience
. 2020 Nov;
23(11):101761.
PMID: 33251492
ATP is required for mammalian cells to remain viable and to perform genetically programmed functions. Maintenance of the ΔG' hydrolysis of -56 kJ/mole is the endpoint of both genetic and...
8.
Seyfried T, Mukherjee P, Iyikesici M, Slocum A, Kalamian M, Spinosa J, et al.
Front Nutr
. 2020 Mar;
7:21.
PMID: 32219096
Breast cancer remains as a significant cause of morbidity and mortality in women. Ultrastructural and biochemical evidence from breast biopsy tissue and cancer cells shows mitochondrial abnormalities that are incompatible...
9.
Mukherjee P, Augur Z, Li M, Hill C, Greenwood B, Domin M, et al.
Commun Biol
. 2019 Jun;
2:200.
PMID: 31149644
Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective therapy for decades. Although glucose and glutamine are the major fuels that drive GBM growth and invasion,...
10.
Seyfried T, Shelton L, Arismendi-Morillo G, Kalamian M, Elsakka A, Maroon J, et al.
Neurochem Res
. 2019 Apr;
44(10):2392-2404.
PMID: 31025151
No major advances have been made in improving overall survival for glioblastoma (GBM) in almost 100 years. The current standard of care (SOC) for GBM involves immediate surgical resection followed...