Leanne C Huysentruyt
Overview
Explore the profile of Leanne C Huysentruyt including associated specialties, affiliations and a list of published articles.
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17
Citations
1025
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Recent Articles
1.
Seyfried T, Huysentruyt L
Crit Rev Oncog
. 2012 Dec;
18(1-2):43-73.
PMID: 23237552
Metastasis involves the spread of cancer cells from the primary tumor to surrounding tissues and to distant organs and is the primary cause of cancer morbidity and mortality. In order...
2.
Lamers S, Fogel G, Singer E, Salemi M, Nolan D, Huysentruyt L, et al.
Int Rev Immunol
. 2012 Dec;
31(6):432-50.
PMID: 23215766
Combined anti-retroviral therapy (cART) has significantly reduced the number of AIDS-associated illnesses and changed the course of HIV-1 disease in developed countries. Despite the ability of cART to maintain high...
3.
Seyfried T, Marsh J, Shelton L, Huysentruyt L, Mukherjee P
Epilepsy Res
. 2011 Sep;
100(3):310-26.
PMID: 21885251
Malignant brain cancer persists as a major disease of morbidity and mortality. The failure to recognize brain cancer as a disease of energy metabolism has contributed in large part to...
4.
Huysentruyt L, Akgoc Z, Seyfried T
ASN Neuro
. 2011 Aug;
3(4).
PMID: 21834792
Most malignant brain tumours contain various numbers of cells with characteristics of activated or dysmorphic macrophages/microglia. These cells are generally considered part of the tumour stroma and are often described...
5.
Lamers S, Fogel G, Huysentruyt L, McGrath M
Curr HIV Res
. 2010 Nov;
8(8):638-40.
PMID: 21067513
This letter refers to the recent demonstration that HIV-1 infected macrophages form specialized conduits that connect to B-cells (1). The conduit selectively transports the HIV-1 nef protein, providing nef with...
6.
Lamers S, Gray R, Salemi M, Huysentruyt L, McGrath M
Infect Genet Evol
. 2010 Nov;
11(1):31-7.
PMID: 21055482
Brain infection by the human immunodeficiency virus type 1 (HIV-1) has been investigated in many reports with a variety of conclusions concerning the time of entry and degree of viral...
7.
Huysentruyt L, Seyfried T
Cancer Metastasis Rev
. 2010 Sep;
29(4):695-707.
PMID: 20839033
Emerging evidence suggests that many metastatic cancers arise from cells of the myeloid/macrophage lineage regardless of the primary tissue of origin. A myeloid origin of metastatic cancer stands apart from...
8.
Seyfried T, Kiebish M, Marsh J, Shelton L, Huysentruyt L, Mukherjee P
Biochim Biophys Acta
. 2010 Sep;
1807(6):577-94.
PMID: 20804725
Malignant brain tumors are a significant health problem in children and adults. Conventional therapeutic approaches have been largely unsuccessful in providing long-term management. As primarily a metabolic disease, malignant brain...
9.
Shelton L, Huysentruyt L, Mukherjee P, Seyfried T
ASN Neuro
. 2010 Jul;
2(3):e00038.
PMID: 20664705
GBM (glioblastoma multiforme) is the most aggressive and invasive form of primary human brain cancer. We recently developed a novel brain cancer model in the inbred VM mouse strain that...
10.
Shelton L, Huysentruyt L, Seyfried T
Int J Cancer
. 2010 May;
127(10):2478-85.
PMID: 20473919
Metastatic cancer is a major cause of morbidity and mortality. Current therapeutic options consist of chemotherapy, radiation or targeted therapies. However, these therapies are often toxic, effective over a small...