Derek C Lee
Overview
Explore the profile of Derek C Lee including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
15
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0
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Recent Articles
1.
Duraj T, Kalamian M, Zuccoli G, Maroon J, DAgostino D, Scheck A, et al.
BMC Med
. 2024 Dec;
22(1):578.
PMID: 39639257
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a universally lethal prognosis despite maximal standard therapies. Here, we present a consensus treatment protocol based on the...
2.
Lee D, Ta L, Mukherjee P, Duraj T, Domin M, Greenwood B, et al.
ASN Neuro
. 2024 Dec;
16(1):2422268.
PMID: 39621724
Energy is necessary for tumor cell viability and growth. Aerobic glucose-driven lactic acid fermentation is a common metabolic phenotype seen in most cancers including malignant gliomas. This metabolic phenotype is...
3.
Williams Z, Imedio A, Gaucherand L, Lee D, Mostafa S, Phelan J, et al.
Elife
. 2024 Jul;
13.
PMID: 39037763
HERV-K(HML-2), the youngest clade of human endogenous retroviruses (HERVs), includes many intact or nearly intact proviruses, but no replication competent HML-2 proviruses have been identified in humans. HML-2-related proviruses are...
4.
Seyfried T, Mukherjee P, Lee D, Ta L, Nations L
Front Nutr
. 2023 Apr;
10:1157517.
PMID: 37057065
Background: Mast cell tumors (MCT) are common neoplasms in dogs and are similar to most other malignant cancers in requiring glucose for growth, regardless of histological grade. Ketogenic metabolic therapy...
5.
Seyfried T, Arismendi-Morillo G, Zuccoli G, Lee D, Duraj T, Elsakka A, et al.
Front Oncol
. 2022 Sep;
12:968351.
PMID: 36059707
Glioblastoma (GBM), similar to most cancers, is dependent on fermentation metabolism for the synthesis of biomass and energy (ATP) regardless of the cellular or genetic heterogeneity seen within the tumor....
6.
Lee D, Vali K, Baldwin S, Divino J, Feliciano J, Fequiere J, et al.
Front Neurosci
. 2019 Nov;
13:1140.
PMID: 31736687
Traumatic brain injury (TBI), caused by repeated concussive head trauma can induce chronic traumatic encephalopathy (CTE), a neurodegenerative disease featuring behavioral symptoms ranging from cognitive deficits to elevated aggression. In...