Probir Chakravarty
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Explore the profile of Probir Chakravarty including associated specialties, affiliations and a list of published articles.
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90
Citations
5421
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Recent Articles
11.
Major J, Crotta S, Finsterbusch K, Chakravarty P, Shah K, Frederico B, et al.
Nature
. 2023 Aug;
621(7980):813-820.
PMID: 37587341
Disruption of the lung endothelial-epithelial cell barrier following respiratory virus infection causes cell and fluid accumulation in the air spaces and compromises vital gas exchange function. Endothelial dysfunction can exacerbate...
12.
Frederico B, Martins I, Chapela D, Gasparrini F, Chakravarty P, Ackels T, et al.
Dev Cell
. 2022 Aug;
57(16):1957-1975.e9.
PMID: 35998585
Cells with latent stem ability can contribute to mammalian tissue regeneration after damage. Whether the central nervous system (CNS) harbors such cells remains controversial. Here, we report that DNGR-1 lineage...
13.
Perdrix Rosell A, Maiques O, Martin J, Chakravarty P, Ombrato L, Sanz-Moreno V, et al.
Cancer Lett
. 2022 Jul;
544:215800.
PMID: 35803476
Cancer cells thrive when embedded in a fine-tuned cellular and extracellular environment or tumour microenvironment (TME). There is a general understanding of a co-evolution between cancer cells and their surrounding...
14.
Shah K, Maradana M, Delas M, Metidji A, Graelmann F, Llorian M, et al.
Nat Commun
. 2022 Apr;
13(1):1827.
PMID: 35383166
The aryl hydrocarbon receptor (AHR) is an environmental sensor that integrates microbial and dietary cues to influence physiological processes within the intestinal microenvironment, protecting against colitis and colitis-associated colorectal cancer...
15.
DAvola A, Legrave N, Tajan M, Chakravarty P, Shearer R, King H, et al.
J Clin Invest
. 2022 Mar;
132(9).
PMID: 35316216
The synthesis of serine from glucose is a key metabolic pathway supporting cellular proliferation in healthy and malignant cells. Despite this, the role that this aspect of metabolism plays in...
16.
Romani P, Nirchio N, Arboit M, Barbieri V, Tosi A, Michielin F, et al.
Nat Cell Biol
. 2022 Feb;
24(2):168-180.
PMID: 35165418
Metastatic breast cancer cells disseminate to organs with a soft microenvironment. Whether and how the mechanical properties of the local tissue influence their response to treatment remains unclear. Here we...
17.
Blair L, Pattison M, Chakravarty P, Papoutsopoulou S, Bakiri L, Wagner E, et al.
J Immunol
. 2022 Jan;
208(4):941-954.
PMID: 35082159
TPL-2 kinase plays an important role in innate immunity, activating ERK1/2 MAPKs in myeloid cells following TLR stimulation. We investigated how TPL-2 controls transcription in TLR4-stimulated mouse macrophages. TPL-2 activation...
18.
Kanagaraj R, Mitter R, Kantidakis T, Edwards M, Benitez A, Chakravarty P, et al.
Proc Natl Acad Sci U S A
. 2022 Jan;
119(4).
PMID: 35042798
Mutations in the gene, which encodes Senataxin, are associated with the progressive neurodegenerative diseases ataxia with oculomotor apraxia 2 (AOA2) and amyotrophic lateral sclerosis 4 (ALS4). To identify the causal...
19.
Morini E, Gao D, Logan E, Salani M, Krauson A, Chekuri A, et al.
J Genet Genomics
. 2021 Dec;
49(7):654-665.
PMID: 34896608
Familial dysautonomia (FD), a hereditary sensory and autonomic neuropathy, is caused by a mutation in the Elongator complex protein 1 (ELP1) gene that leads to a tissue-specific reduction of ELP1...
20.
Tabone O, Verma R, Singhania A, Chakravarty P, Branchett W, Graham C, et al.
J Exp Med
. 2021 Sep;
218(10).
PMID: 34491266
Blood transcriptomics have revealed major characteristics of the immune response in active TB, but the signature early after infection is unknown. In a unique clinically and temporally well-defined cohort of...