Pradipta Ray
Overview
Explore the profile of Pradipta Ray including associated specialties, affiliations and a list of published articles.
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12
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4330
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Recent Articles
1.
Amatangelo M, Flynt E, Stong N, Ray P, Van Oekelen O, Wang M, et al.
Cell Rep Med
. 2024 May;
5(6):101571.
PMID: 38776914
Iberdomide is a next-generation cereblon (CRBN)-modulating agent in the clinical development in multiple myeloma (MM). The analysis of biomarker samples from relapsed/refractory patients enrolled in CC-220-MM-001 (ClinicalTrials.gov: NCT02773030), a phase...
2.
Hall B, Macdonald E, Cassidy M, Yun S, Sapio M, Ray P, et al.
Sci Rep
. 2022 Mar;
12(1):4729.
PMID: 35304484
Pathological sensations caused by peripheral painful neuropathy occurring in Type 2 diabetes mellitus (T2DM) are often described as 'sharp' and 'burning' and are commonly spontaneous in origin. Proposed etiologies implicate...
3.
Sathe A, Zhang Y, Ma X, Ray P, Cadinu D, Wang Y, et al.
IEEE Life Sci Lett
. 2021 Mar;
1(3):30-33.
PMID: 33758771
Aberrant DNA methylation has long been implicated in cancers. In this work we present a highly discriminative DNA methylation biomarker for non-small cell lung cancers and fourteen other cancers. Based...
4.
North R, Li Y, Ray P, Rhines L, Tatsui C, Rao G, et al.
Brain
. 2019 Mar;
142(5):1215-1226.
PMID: 30887021
Neuropathic pain encompasses a diverse array of clinical entities affecting 7-10% of the population, which is challenging to adequately treat. Several promising therapeutics derived from molecular discoveries in animal models...
5.
Ray P, Torck A, Quigley L, Wangzhou A, Neiman M, Rao C, et al.
Pain
. 2018 Mar;
159(7):1325-1345.
PMID: 29561359
Molecular neurobiological insight into human nervous tissues is needed to generate next-generation therapeutics for neurological disorders such as chronic pain. We obtained human dorsal root ganglia (hDRG) samples from organ...
6.
Pavlovic M, Ray P, Pavlovic K, Kotamarti A, Chen M, Zhang M
Bioinformatics
. 2017 May;
33(19):2986-2994.
PMID: 28505334
Motivation: 5-Methylcytosine and 5-Hydroxymethylcytosine in DNA are major epigenetic modifications known to significantly alter mammalian gene expression. High-throughput assays to detect these modifications are expensive, labor-intensive, unfeasible in some contexts...
7.
Leung D, Jung I, Rajagopal N, Schmitt A, Selvaraj S, Lee A, et al.
Nature
. 2015 Feb;
518(7539):350-354.
PMID: 25693566
Allelic differences between the two homologous chromosomes can affect the propensity of inheritance in humans; however, the extent of such differences in the human genome has yet to be fully...
8.
Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, et al.
Nature
. 2015 Feb;
518(7539):317-30.
PMID: 25693563
The reference human genome sequence set the stage for studies of genetic variation and its association with human disease, but epigenomic studies lack a similar reference. To address this need,...
9.
Distinct and predictive histone lysine acetylation patterns at promoters, enhancers, and gene bodies
Rajagopal N, Ernst J, Ray P, Wu J, Zhang M, Kellis M, et al.
G3 (Bethesda)
. 2014 Aug;
4(11):2051-63.
PMID: 25122670
In eukaryotic cells, histone lysines are frequently acetylated. However, unlike modifications such as methylations, histone acetylation modifications are often considered redundant. As such, the functional roles of distinct histone acetylations...
10.
Xie W, Schultz M, Lister R, Hou Z, Rajagopal N, Ray P, et al.
Cell
. 2013 May;
153(5):1134-48.
PMID: 23664764
Epigenetic mechanisms have been proposed to play crucial roles in mammalian development, but their precise functions are only partially understood. To investigate epigenetic regulation of embryonic development, we differentiated human...