» Authors » Pomila Singh

Pomila Singh

Explore the profile of Pomila Singh including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 32
Citations 730
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Kantara C, Singh P
Methods Mol Biol . 2024 Mar; 2777:205-218. PMID: 38478346
Measuring circulating tumor cells (CTCs) or circulating cancer stem cells (CCSCs) in blood, which shed from primary tumors, is a noninvasive method to screen and/or diagnose patients with a high...
2.
Park S, Kim J, Choi J, Kim J, Lee C, Singh P, et al.
Clin Cancer Res . 2018 Nov; 25(4):1415-1429. PMID: 30446587
Purpose: Niclosamide, an FDA-approved anthelmintic drug, has been characterized as a potent Wnt inhibitor that can suppress tumor growth and cancer stem-like cell (CSC) populations. However, the underlying molecular mechanisms...
3.
Hsu C, Sowers M, Hsu W, Eyzaguirre E, Qiu S, Chao C, et al.
Trends Cancer Res . 2018 Aug; 12:111-132. PMID: 30147278
Colorectal cancer (CRC) is a major health challenge worldwide. Factors thought to be important in CRC etiology include diet, microbiome, exercise, obesity, a history of colon inflammation and family history....
4.
Sarkar S, OConnell M, Okugawa Y, Lee B, Toiyama Y, Kusunoki M, et al.
Mol Cancer Res . 2017 Aug; 15(12):1678-1691. PMID: 28851816
The 5' (α)-promoter of the human doublecortin-like kinase 1 () gene becomes epigenetically silenced during colon carcinogenesis, resulting in loss of expression of the canonical long(L)-isoform1 (DCLK1-L) in human colon...
5.
Sarkar S, Popov V, OConnell M, Stevenson H, Lee B, Obeid R, et al.
Lab Invest . 2017 Apr; 97(10):1245-1261. PMID: 28414327
DCLK1 expression is critically required for maintaining growth of human colon cancer cells (hCCCs). Human colorectal tumors (CRCs) and hCCCs express a novel short isoform of DCLK1 (DCLK1-S; isoform 2)...
6.
Singh P, OConnell M, Shubhashish S
Stem Cell Investig . 2016 Oct; 3:51. PMID: 27777940
Colorectal carcinogenesis is a multi-step process. While ~25% of colorectal cancers (CRCs) arise in patients with a family history (genetic predisposition), ~75% of CRCs are due to age-associated accumulation of...
7.
Huynh P, Beswick E, Coronado Y, Johnson P, OConnell M, Watts T, et al.
Int J Cancer . 2015 Nov; 138(8):1971-81. PMID: 26595254
IL-6 is a pleiotropic cytokine increased in CRC and known to directly promote tumor growth. Colonic myofibroblasts/fibroblasts (CMFs or stromal cells) are CD90(+) innate immune cells representing up to 30%...
8.
OConnell M, Sarkar S, Luthra G, Okugawa Y, Toiyama Y, Gajjar A, et al.
Sci Rep . 2015 Oct; 5:14983. PMID: 26447334
DCLK1 specifically marks colon/pancreatic cancers in mice, and is expressed by human colon adenocarcinomas (hCRCs). Down-regulation of DCLK1 results in loss of cancer-stem-cells (CSCs), and inhibits spheroidal/xenograft growths from hCRC-cells....
9.
Kantara C, Moya S, Houchen C, Umar S, Ullrich R, Singh P, et al.
Lab Invest . 2015 Aug; 95(11):1222-33. PMID: 26280221
In recent years, increasing threats of radiation exposure and nuclear disasters have become a significant concern for the United States and countries worldwide. Exposure to high doses of radiation triggers...
10.
Kantara C, OConnell M, Luthra G, Gajjar A, Sarkar S, Ullrich R, et al.
Lab Invest . 2014 Oct; 95(1):100-12. PMID: 25347154
Cancer stem cells (CSCs) are believed to be resistant to currently available therapies and may be responsible for relapse of cancer in patients. Measuring circulating tumor cells (CTCs) in the...