Pier Andrea Borea
Overview
Explore the profile of Pier Andrea Borea including associated specialties, affiliations and a list of published articles.
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Articles
189
Citations
4117
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Recent Articles
21.
Merighi S, Gessi S, Bencivenni S, Battistello E, Vincenzi F, Setti S, et al.
Cytokine
. 2019 Aug;
125:154777.
PMID: 31400640
Literature studies suggest important protective effects of low-frequency, low-energy pulsed electromagnetic fields (PEMFs) on inflammatory pathways affecting joint and cerebral diseases. However, it is not clear on which bases they...
22.
Merighi S, Battistello E, Giacomelli L, Varani K, Vincenzi F, Borea P, et al.
Expert Opin Ther Targets
. 2019 Jun;
23(8):669-678.
PMID: 31189400
: There is a vicious cycle of tumor hypoxia, high adenosine levels, immune suppression and cancer growth that involves the use of adenosine receptor ligands in tumors. After several years...
23.
Gessi S, Merighi S, Bencivenni S, Battistello E, Vincenzi F, Setti S, et al.
J Cell Physiol
. 2019 Jan;
234(9):15089-15097.
PMID: 30656694
Low-energy low-frequency pulsed electromagnetic fields (PEMFs) exert several protective effects, such as the regulation of kinases, transcription factors as well as cell viability in both central and peripheral biological systems....
24.
Navarro G, Varani K, Reyes-Resina I, Sanchez de Medina V, Rivas-Santisteban R, Sanchez-Carnerero Callado C, et al.
Front Pharmacol
. 2018 Jul;
9:632.
PMID: 29977202
Cannabigerol (CBG) is one of the major phytocannabinoids present in L. that is attracting pharmacological interest because it is non-psychotropic and is abundant in some industrial hemp varieties. The aim...
25.
Varano F, Catarzi D, Vincenzi F, Falsini M, Pasquini S, Borea P, et al.
Eur J Med Chem
. 2018 Jun;
155:552-561.
PMID: 29909340
This paper describes the synthesis and characterization of N-(hetero)arylalkyl-substituted-thiazolo [5,4-d]pyrimidine-5,7-diamine derivatives (4-19) as novel human (h) A adenosine receptor (AR) inverse agonists. Competition binding and cyclic AMP assays indicate that...
26.
Borea P, Gessi S, Merighi S, Vincenzi F, Varani K
Physiol Rev
. 2018 Jun;
98(3):1591-1625.
PMID: 29848236
Adenosine is a ubiquitous endogenous autacoid whose effects are triggered through the enrollment of four G protein-coupled receptors: A, A, A, and A. Due to the rapid generation of adenosine...
27.
Gessi S, Bencivenni S, Battistello E, Vincenzi F, Colotta V, Catarzi D, et al.
Front Pharmacol
. 2017 Dec;
8:888.
PMID: 29249971
Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A, A, A, and A receptor (AR) subtypes, plays crucial roles in tumor development. Adenosine has contrasting effects on cell...
28.
Martinez-Pinilla E, Varani K, Reyes-Resina I, Angelats E, Vincenzi F, Ferreiro-Vera C, et al.
Front Pharmacol
. 2017 Nov;
8:744.
PMID: 29109685
The mechanism of action of cannabidiol (CBD), the main non-psychotropic component of L., is not completely understood. First assumed that the compound was acting via cannabinoid CB receptors (CBRs) it...
29.
Ossato A, Uccelli L, Bilel S, Canazza I, Di Domenico G, Pasquali M, et al.
Front Psychiatry
. 2017 Aug;
8:130.
PMID: 28824464
JWH-018 and AKB48 are two synthetic cannabinoids (SCBs) belonging to different structural classes and illegally marketed as incense, herbal preparations, or chemical supply for theirs psychoactive cannabis-like effects. Clinical reports...
30.
Jacobson K, Merighi S, Varani K, Borea P, Baraldi S, Aghazadeh Tabrizi M, et al.
Med Res Rev
. 2017 Jul;
38(4):1031-1072.
PMID: 28682469
The A adenosine receptor (A AR) subtype is a novel, promising therapeutic target for inflammatory diseases, such as rheumatoid arthritis (RA) and psoriasis, as well as liver cancer. A AR...