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Physiological Reviews

Physiological Reviews is a prestigious scientific journal that publishes comprehensive and authoritative reviews on various aspects of physiology. It covers a wide range of topics, including cellular and molecular physiology, organ systems, and integrative physiology. With its rigorous peer-review process, the journal provides a valuable resource for researchers, educators, and students seeking in-depth knowledge and understanding of physiological mechanisms and their implications in health and disease.

Details
Abbr. Physiol Rev
Start 1921
End Continuing
Frequency Quarterly
p-ISSN 0031-9333
e-ISSN 1522-1210
Country United States
Language English
Specialty Physiology
Metrics
h-index / Ranks: 83 388
SJR / Ranks: 63 10821
CiteScore / Ranks: 16 79.50
JIF / Ranks: 68 33.6
Recent Articles
1.
Palese F, Rakotobe M, Zurzolo C
Physiol Rev . 2025 Mar; PMID: 40067081
Tunneling nanotubes (TNTs) are thin tubular membrane protrusions that connect distant cells, generating a complex cellular network. Over the past few decades, research on TNTs has provided important insights into...
2.
Lemche E, Hortobagyi T, Kiecker C, Turkheimer F
Physiol Rev . 2025 Mar; PMID: 40062731
Recent decades have described in-parallel neuropathological mechanisms, increasing the risk for developing late-onset Alzheimer's dementia (LOAD) in type 2 diabetes mellitus (T2DM), however, still little is known of the role...
3.
Jaitovich A, Hall J
Physiol Rev . 2025 Feb; PMID: 39982115
During critical illness, systemic inflammation causes organ-specific metabolic changes. In the immune and inflammatory compartments, predominantly anabolic reprogramming supports cellular replication and inflammatory response execution. Pari passu, catabolism of adipose...
4.
Baston E, Garcia-Agullo J, Peinado H
Physiol Rev . 2025 Feb; PMID: 39981994
Disruption of cellular communication that regulates normal physiology is often key factor in the development of disease, including cancer. Extracellular vesicles (EVs) are mediators of cell-cell communication, modulating local and...
5.
Markus H, Joutel A
Physiol Rev . 2025 Feb; PMID: 39965059
Cerebral small vessel disease (cSVD) is the broadly accepted term nowadays to designate a heterogeneous group of diseases caused by in situ damages of small brain vessels commonly related to...
6.
Boletta A, Caplan M
Physiol Rev . 2025 Feb; PMID: 39938884
Polycystic Kidney Disease (PKD) encompasses a class of disorders presenting with bilateral cyst formation in the kidney. PKD can be inherited as a dominant (ADPKD) or a recessive (ARPKD) trait,...
7.
Chhabra K, Shoemaker R, Herath C, Thomas M, Filipeanu C, Lazartigues E
Physiol Rev . 2025 Feb; PMID: 39918873
Angiotensin Converting Enzyme 2 (ACE2) was discovered 25 years ago as a negative regulator of renin-angiotensin system, opposing the effects of angiotensin-II. Beyond its well-demonstrated roles in cardiovascular regulation and...
8.
Costa D, Santosa S, Jensen M
Physiol Rev . 2025 Jan; PMID: 39869194
Adult males and females have markedly different body composition, energy expenditure, and have different degrees of risk for metabolic diseases. A major aspect of metabolic regulation involves the appropriate storage...
9.
Gerber M, Cheval B, Cody R, Colledge F, Hohberg V, Klimentidis Y, et al.
Physiol Rev . 2025 Jan; PMID: 39854639
Physical activity is a meaningful part of life, which starts before birth and lasts until death. There are many health benefits to be derived from physical activity, hence, regular engagement...
10.
Levin B, Geary N, Lutz T
Physiol Rev . 2025 Jan; PMID: 39824509
Metabolic energy stored mainly as adipose tissue is homeostatically regulated. There is strong evidence that human body weight () is physiologically regulated, i.e. maintained within a relatively narrow range in...