Philippe Lesnik
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Explore the profile of Philippe Lesnik including associated specialties, affiliations and a list of published articles.
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Articles
64
Citations
2426
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Recent Articles
1.
Dahik V, Kc P, Materne C, Reydellet C, Lhomme M, Cruciani-Guglielmacci C, et al.
Sci Transl Med
. 2024 Dec;
16(777):eadi6682.
PMID: 39661702
The mechanisms governing adipose tissue macrophage (ATM) metabolic adaptation during diet-induced obesity (DIO) are poorly understood. In obese adipose tissue, ATMs are exposed to lipid fluxes, which can influence the...
2.
Silvain J, Materne C, Zeitouni M, Procopi N, Guedeney P, Brugier D, et al.
Eur J Prev Cardiol
. 2024 Nov;
PMID: 39506545
Aims: Low cholesterol efflux capacity and elevated levels of Interleukin-1ß (IL-1ß) are both associated with residual cardiovascular risk in patients with acute myocardial infarction (MI) and may be used as...
3.
dHumieres C, Delavy M, Alla L, Ichou F, Gauliard E, Ghozlane A, et al.
Microbiome
. 2024 Mar;
12(1):50.
PMID: 38468305
Background: Antibiotics notoriously perturb the gut microbiota. We treated healthy volunteers either with cefotaxime or ceftriaxone for 3 days, and collected in each subject 12 faecal samples up to day...
4.
Jamgotchian L, Devel L, Thai R, Poupel L, Huby T, Gautier E, et al.
Nanoscale
. 2023 Nov;
15(46):18864-18870.
PMID: 37966726
We report the development of compact and stabilized micelles incorporating a synthetic LXR agonist prodrug for the passive targeting of atherosclerotic lesions and therapeutic intervention. studies showed that the nanohybrid...
5.
Boccara F, Sabouret P, Boileau C, Georges J, Leclercq C, Lesnik P, et al.
Panminerva Med
. 2023 Oct;
66(1):18-26.
PMID: 37851332
Background: Increased level of blood LDL-C has a causal and cumulative effect on advancing atherosclerotic cardiovascular diseases (ASCVD). European guidelines for treating high LDL-C levels have been recently updated. However,...
6.
Marousez L, Ichou F, Lesnik P, Tran L, de Lamballerie M, Gottrand F, et al.
Front Pediatr
. 2023 Oct;
11:1120008.
PMID: 37842027
Sterilized donor milk (DM) is frequently used for feeding preterm infants. To date, the effect of different modes of DM sterilization on short-chain fatty acids (SCFAs) remains unknown. We aimed...
7.
Urbain F, Ponnaiah M, Ichou F, Lhomme M, Materne C, Galier S, et al.
EBioMedicine
. 2023 Sep;
96:104802.
PMID: 37725854
Background: Patients with systemic lupus erythematosus (SLE) exhibit a high risk for cardiovascular diseases (CVD) which is not fully explained by the classical Framingham risk factors. SLE is characterized by...
8.
Guillas I, Lhomme M, Pionneau C, Matheron L, Ponnaiah M, Galier S, et al.
Basic Res Cardiol
. 2023 Aug;
118(1):33.
PMID: 37639039
While low concentrations of high-density lipoprotein-cholesterol (HDL-C) are widely accepted as an independent cardiovascular risk factor, HDL-C-rising therapies largely failed, suggesting the importance of both HDL functions and individual subspecies....
9.
Ma F, Darabi M, Lhomme M, Tubeuf E, Canicio A, Brerault J, et al.
Atherosclerosis
. 2023 Apr;
372:57.
PMID: 37019714
No abstract available.
10.
Martinez-Garcia J, Rainteau D, Humbert L, Lamaziere A, Lesnik P, Chamaillard M
Metabolites
. 2022 May;
12(5).
PMID: 35629894
The behavior and physiology of most organisms are temporally coordinated and aligned with geophysical time by a complex interplay between the master and peripheral clocks. Disruption of such rhythmic physiological...