Wilfried Le Goff
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Explore the profile of Wilfried Le Goff including associated specialties, affiliations and a list of published articles.
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104
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1908
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Recent Articles
1.
Le Goff W, Bourron O, Materne C, Galier S, Phan F, Tan-Chen S, et al.
Cardiovasc Diabetol
. 2025 Feb;
24(1):85.
PMID: 39984928
Background: Sphingosine 1-phosphate (S1P) is a key mediator of lipid signaling with strong immunomodulatory and anti-inflammatory effects. Circulating S1P levels including S1P in high-density lipoproteins (HDL) were demonstrated to be...
2.
High-density lipoprotein-like nanoparticles with cationic cholesterol derivatives for siRNA delivery
Ihnatsyeu-Kachan A, Sharko O, Bekish A, Saichuk A, Zhogla V, Abashkin V, et al.
Biomater Adv
. 2025 Feb;
170:214202.
PMID: 39923604
A new approach to siRNA delivery using high-density lipoprotein-like nanoparticles (HDL NPs) was investigated, incorporating oligoamine and cholesterol-derived cationic lipids (CLs) to associate siRNA with the carrier. Newly designed or...
3.
Dahik V, Kc P, Materne C, Reydellet C, Lhomme M, Cruciani-Guglielmacci C, et al.
Sci Transl Med
. 2024 Dec;
16(777):eadi6682.
PMID: 39661702
The mechanisms governing adipose tissue macrophage (ATM) metabolic adaptation during diet-induced obesity (DIO) are poorly understood. In obese adipose tissue, ATMs are exposed to lipid fluxes, which can influence the...
4.
Silvain J, Materne C, Zeitouni M, Procopi N, Guedeney P, Brugier D, et al.
Eur J Prev Cardiol
. 2024 Nov;
PMID: 39506545
Aims: Low cholesterol efflux capacity and elevated levels of Interleukin-1ß (IL-1ß) are both associated with residual cardiovascular risk in patients with acute myocardial infarction (MI) and may be used as...
5.
Gallo A, Le Goff W, Santos R, Fichtner I, Carugo S, Corsini A, et al.
Eur J Clin Invest
. 2024 Oct;
55(1):e14326.
PMID: 39370572
Background: Maintaining low concentrations of plasma low-density lipoprotein cholesterol (LDLc) over time decreases the number of LDL particles trapped within the artery wall, slows the progression of atherosclerosis and delays...
6.
Galier S, Darabi M, Ma F, Materne C, Guillas I, Le Goff W, et al.
J Am Heart Assoc
. 2024 Jul;
13(15):e034770.
PMID: 39082393
Background: The capacity of high-density lipoprotein cholesterol (HDL) to acquire free cholesterol (FC) from triglyceride-rich lipoproteins during lipoprotein lipase-dependent lipolysis in a process of reverse remnant cholesterol transport, has been...
7.
Suffee N, Le Goff W, Chen J
Front Immunol
. 2024 Mar;
15:1384022.
PMID: 38495875
No abstract available.
8.
Soulat-Dufour L, Ichou F, Ponnaiah M, Lang S, Ederhy S, Adavane-Scheuble S, et al.
Arch Cardiovasc Dis
. 2024 Jan;
117(2):134-142.
PMID: 38290892
Background: Left atrial (LA) strain is a simple marker of LA function. The aim of the study was to evaluate the determinants of atrial cardiomyopathy in AF. Methods: In this...
9.
Jamgotchian L, Devel L, Thai R, Poupel L, Huby T, Gautier E, et al.
Nanoscale
. 2023 Nov;
15(46):18864-18870.
PMID: 37966726
We report the development of compact and stabilized micelles incorporating a synthetic LXR agonist prodrug for the passive targeting of atherosclerotic lesions and therapeutic intervention. studies showed that the nanohybrid...
10.
Laurans L, Mouttoulingam N, Chajadine M, Lavelle A, Diedisheim M, Bacquer E, et al.
Cell Rep
. 2023 Oct;
42(11):113350.
PMID: 37897726
Although high-fat diet (HFD)-induced gut microbiota dysbiosis is known to affect atherosclerosis, the underlying mechanisms remain to be fully explored. Here, we show that the progression of atherosclerosis depends on...