Emmanuel L Gautier
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Explore the profile of Emmanuel L Gautier including associated specialties, affiliations and a list of published articles.
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65
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6902
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Recent Articles
1.
Lecoutre S, Rebiere C, Maqdasy S, Lambert M, Dussaud S, Abatan J, et al.
Nat Rev Endocrinol
. 2025 Jan;
PMID: 39757324
Adipose tissue demonstrates considerable plasticity and heterogeneity, enabling metabolic, cellular and structural adaptations to environmental signals. This adaptability is key for maintaining metabolic homeostasis. Impaired adipose tissue plasticity can lead...
2.
Genest M, Kinugasa S, Roger E, Boutin L, Placier S, Figueroa S, et al.
Mol Med
. 2024 Dec;
30(1):261.
PMID: 39707203
Background: We have previously reported that the gap junction protein connexin 43 (Cx43) was upregulated in chronic renal disease in humans and rodents and plays a crucial role in the...
3.
Murcy F, Borowczyk C, Gourion-Arsiquaud S, Torrino S, Ouahrouche N, Barouillet T, et al.
Nat Cardiovasc Res
. 2024 Nov;
3(12):1454-1467.
PMID: 39562782
Metabolic dysregulation, including perturbed glutamine-glutamate homeostasis, is common among patients with cardiovascular diseases, but the underlying mechanisms remain largely unknown. Using the human MESA cohort, here we show that plasma...
4.
Arbogast F, Sal-Carro R, Boufenghour W, Frenger Q, Bouis D, Filippi De La Palavesa L, et al.
J Cell Biol
. 2024 Nov;
224(2).
PMID: 39535446
Macroautophagy (often-named autophagy), a catabolic process involving autophagy-related (Atg) genes, prevents the accumulation of harmful cytoplasmic components and mobilizes energy reserves in long-lived and self-renewing cells. Autophagy deficiency affects antigen...
5.
Fima R, Dussaud S, Benbida C, Blanchet M, Lanthiez F, Poupel L, et al.
Nat Commun
. 2024 Sep;
15(1):8341.
PMID: 39333539
Hypercholesterolemia is a major risk factor for atherosclerosis and associated cardiovascular diseases. The liver plays a key role in the regulation of plasma cholesterol levels and hosts a large population...
6.
Gelineau A, Marcelin G, Ouhachi M, Dussaud S, Voland L, Manuel R, et al.
Nat Commun
. 2024 Jun;
15(1):5413.
PMID: 38926424
Diet composition impacts metabolic health and is now recognized to shape the immune system, especially in the intestinal tract. Nutritional imbalance and increased caloric intake are induced by high-fat diet...
7.
Lana J, Oliveira M, Silveira A, Yamada L, Costa K, da Silva S, et al.
Int J Obes (Lond)
. 2024 Mar;
48(7):964-972.
PMID: 38459259
Background/objectives: Proinflammatory cytokines are increased in obese adipose tissue, including inflammasome key masters. Conversely, IL-18 protects against obesity and metabolic dysfunction. We focused on the IL-18 effect in controlling adipose...
8.
Roubeix C, Nous C, Augustin S, Ronning K, Mathis T, Blond F, et al.
J Neuroinflammation
. 2024 Jan;
21(1):22.
PMID: 38233865
Age-related macular degeneration (AMD) is invariably associated with the chronic accumulation of activated mononuclear phagocytes in the subretinal space. The mononuclear phagocytes are composed of microglial cells but also of...
9.
Regnier P, Vetillard M, Bansard A, Pierre E, Li X, Cagnard N, et al.
Cell Rep Med
. 2023 Dec;
4(12):101256.
PMID: 38118422
FLT3-L-dependent classical dendritic cells (cDCs) recruit anti-tumor and tumor-protecting lymphocytes. We evaluate cancer growth in mice with low, normal, or high levels of cDCs. Paradoxically, both low or high numbers...
10.
Fanlo L, Gomez-Gonzalez S, Rozalen C, Perez-Nunez I, Sangrador I, Tomas-Daza L, et al.
Oncogene
. 2023 Jun;
42(28):2218-2233.
PMID: 37301928
Neuroblastoma is a pediatric cancer that can present as low- or high-risk tumors (LR-NBs and HR-NBs), the latter group showing poor prognosis due to metastasis and strong resistance to current...