Short-chain Fatty Acids Levels in Human Milk Are Not Affected by Holder Pasteurization and High Hydrostatic Pressure Processing

Overview

Journal Front Pediatr

Specialty Pediatrics

Date 2023 Oct 16

PMID 37842027

Authors

Lucie Marousez

Farid Ichou

Philippe Lesnik

Lea Chantal Tran

Marie de Lamballerie

Frederic Gottrand

Delphine Ley

Jean Lesage

Affiliations

Soon will be listed here.

Abstract

Sterilized donor milk (DM) is frequently used for feeding preterm infants. To date, the effect of different modes of DM sterilization on short-chain fatty acids (SCFAs) remains unknown. We aimed to quantify SCFAs in DM samples after two types of milk sterilization: the Holder pasteurization (HoP) and a high hydrostatic pressure (HP) processing. Eight pooled DM samples were sterilized by HoP (62.5°C for 30 min) or processed by HP (350 MPa at 38°C). Raw DM was used as control. Six SCFAs were quantified by gas chromatography/mass spectrometry. Compared to raw milk, both HoP and HP treatment did not significantly modulate the concentration of acetate, butyrate, propionate and isovalerate in DM. Valerate and isobutyrate were undetectable in DM samples. In conclusion, both HoP and HP processing preserved milk SCFAs at their initial levels in raw human milk.

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