Peter I Croucher
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Explore the profile of Peter I Croucher including associated specialties, affiliations and a list of published articles.
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97
Citations
4238
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Recent Articles
1.
Kim A, Taylor V, Castro-Martinez A, Dhakal S, Zamerli A, Mohanty S, et al.
J Bone Miner Res
. 2025 Jan;
40(3):413-427.
PMID: 39846954
Rebound bone loss following denosumab discontinuation is an important barrier in the effective long-term treatment of skeletal disorders. This is driven by increased osteoclastic bone resorption following the offset of...
2.
Phan T, Weilbaecher K, Aft R, Croucher P, Chaffer C
Cancer Discov
. 2024 Apr;
14(4):643-647.
PMID: 38571433
Understandably, conventional therapeutic strategies have focused on controlling primary tumors. We ask whether the cost of such strategies is actually an increased likelihood of metastatic relapse.
3.
Gunter H, Youlten S, Reis A, McCubbin T, Madala B, Wong T, et al.
Nat Commun
. 2024 Mar;
15(1):2480.
PMID: 38509097
The expression of genes encompasses their transcription into mRNA followed by translation into protein. In recent years, next-generation sequencing and mass spectrometry methods have profiled DNA, RNA and protein abundance...
4.
Kim A, Taylor V, Castro-Martinez A, Dhakal S, Zamerli A, Mohanty S, et al.
J Bone Miner Res
. 2024 Mar;
39(4):484-497.
PMID: 38477789
Rebound bone loss following denosumab discontinuation is an important clinical challenge. Current treatment strategies to prevent this fail to suppress the rise and overshoot in osteoclast-mediated bone resorption. In this...
5.
Kyaw W, Chai R, Khoo W, Goldstein L, Croucher P, Murray J, et al.
Bioinformatics
. 2023 Dec;
39(12).
PMID: 38113422
Motivation: Cell fate is commonly studied by profiling the gene expression of single cells to infer developmental trajectories based on expression similarity, RNA velocity, or statistical mechanical properties. However, current...
6.
Bhattacharyya N, Kyaw W, McDonald M, Dhenni R, Grootveld A, Xiao Y, et al.
Nat Protoc
. 2023 Oct;
18(12):3856-3880.
PMID: 37857852
Intravital two-photon microscopy enables deep-tissue imaging at high temporospatial resolution in live animals. However, the endosteal bone compartment and underlying bone marrow pose unique challenges to optical imaging as light...
7.
Simic M, Mohanty S, Xiao Y, Cheng T, Taylor V, Charlat O, et al.
J Bone Miner Res
. 2023 Mar;
38(6):814-828.
PMID: 36987921
An imbalance between bone resorption and bone formation underlies the devastating osteolytic lesions and subsequent fractures seen in more than 90% of multiple myeloma (MM) patients. Currently, Wnt-targeted therapeutic agents...
8.
Grootveld A, Kyaw W, Panova V, Lau A, Ashwin E, Seuzaret G, et al.
Cell
. 2023 Mar;
186(6):1144-1161.e18.
PMID: 36868219
Germinal centers (GCs) that form within lymphoid follicles during antibody responses are sites of massive cell death. Tingible body macrophages (TBMs) are tasked with apoptotic cell clearance to prevent secondary...
9.
Phetsouphanh C, Khoo W, Jackson K, Klemm V, Howe A, Aggarwal A, et al.
Front Immunol
. 2022 Dec;
13:1032911.
PMID: 36544780
Background: Long-term immunity to SARS-CoV-2 infection, including neutralizing antibodies and T cell-mediated immunity, is required in a very large majority of the population in order to reduce ongoing disease burden....
10.
Khoo W, Jackson K, Phetsouphanh C, Zaunders J, Alquicira-Hernandez J, Yazar S, et al.
Clin Immunol
. 2022 Dec;
246:109209.
PMID: 36539107
Children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) develop less severe coronavirus disease 2019 (COVID-19) than adults. The mechanisms for the age-specific differences and the implications for infection-induced...