Sindhu T Mohanty
Overview
Explore the profile of Sindhu T Mohanty including associated specialties, affiliations and a list of published articles.
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18
Citations
1013
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Recent Articles
1.
Kim A, Taylor V, Castro-Martinez A, Dhakal S, Zamerli A, Mohanty S, et al.
J Bone Miner Res
. 2025 Jan;
40(3):413-427.
PMID: 39846954
Rebound bone loss following denosumab discontinuation is an important barrier in the effective long-term treatment of skeletal disorders. This is driven by increased osteoclastic bone resorption following the offset of...
2.
Diamond T, Bryant C, Quinn R, Mohanty S, Bonar F, Baldock P, et al.
JBMR Plus
. 2023 Aug;
7(8):e10734.
PMID: 37614304
A 71-year-old man was referred for evaluation of incidental generalized osteosclerosis. He was found to have a high bone mass (HBM) with an elevated lumbar spine bone mineral density (BMD)...
3.
Simic M, Mohanty S, Xiao Y, Cheng T, Taylor V, Charlat O, et al.
J Bone Miner Res
. 2023 Mar;
38(6):814-828.
PMID: 36987921
An imbalance between bone resorption and bone formation underlies the devastating osteolytic lesions and subsequent fractures seen in more than 90% of multiple myeloma (MM) patients. Currently, Wnt-targeted therapeutic agents...
4.
Youlten S, Kemp J, Logan J, Ghirardello E, Sergio C, Dack M, et al.
Nat Commun
. 2021 May;
12(1):2444.
PMID: 33953184
Osteocytes are master regulators of the skeleton. We mapped the transcriptome of osteocytes from different skeletal sites, across age and sexes in mice to reveal genes and molecular programs that...
5.
McDonald M, Khoo W, Ng P, Xiao Y, Zamerli J, Thatcher P, et al.
Cell
. 2021 Apr;
184(7):1940.
PMID: 33798441
No abstract available.
6.
McDonald M, Khoo W, Ng P, Xiao Y, Zamerli J, Thatcher P, et al.
Cell
. 2021 Feb;
184(5):1330-1347.e13.
PMID: 33636130
Osteoclasts are large multinucleated bone-resorbing cells formed by the fusion of monocyte/macrophage-derived precursors that are thought to undergo apoptosis once resorption is complete. Here, by intravital imaging, we reveal that...
7.
Khoo W, Ledergor G, Weiner A, Roden D, Terry R, McDonald M, et al.
Blood
. 2019 Apr;
134(1):30-43.
PMID: 31023703
The era of targeted therapies has seen significant improvements in depth of response, progression-free survival, and overall survival for patients with multiple myeloma. Despite these improvements in clinical outcome, patients...
8.
Morris J, Kemp J, Youlten S, Laurent L, Logan J, Chai R, et al.
Nat Genet
. 2019 Apr;
51(5):920.
PMID: 30988516
In the version of this article initially published, in Fig. 5a, the data in the right column of 'DAAM2 gRNA1' were incorrectly plotted as circles indicating 'untreated' rather than as...
9.
Morris J, Kemp J, Youlten S, Laurent L, Logan J, Chai R, et al.
Nat Genet
. 2019 Jan;
51(2):258-266.
PMID: 30598549
Osteoporosis is a common aging-related disease diagnosed primarily using bone mineral density (BMD). We assessed genetic determinants of BMD as estimated by heel quantitative ultrasound in 426,824 individuals, identifying 518...
10.
Morse A, Cheng T, Schindeler A, McDonald M, Mohanty S, Kneissel M, et al.
Calcif Tissue Int
. 2018 May;
103(3):298-310.
PMID: 29845410
Dickkopf-1 (DKK1) and sclerostin are antagonists of the Wnt/β-catenin pathway and decreased expression of either results in increased bone formation and mass. As both affect the same signaling pathway, we...