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Scott E Youlten

Explore the profile of Scott E Youlten including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 1045
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Recent Articles
1.
Venkat A, Leone S, Youlten S, Fagerberg E, Attanasio J, Joshi N, et al.
Nat Comput Sci . 2024 Dec; 4(12):955-977. PMID: 39706866
In single-cell sequencing analysis, several computational methods have been developed to map the cellular state space, but little has been done to map or create embeddings of the gene space....
2.
Venkat A, Carlino M, Lawton B, Prasad M, Amodio M, Gibson C, et al.
Genome Res . 2024 Jul; 34(6):837-850. PMID: 38977309
Studies on human parathyroids are generally limited to hyperfunctioning glands owing to the difficulty in obtaining normal human tissue. We therefore obtained non-human primate (NHP) parathyroids to provide a suitable...
3.
Youlten S, Miao L, Hoppe C, Boswell C, Musaev D, Abdelmessih M, et al.
bioRxiv . 2024 May; PMID: 38798464
The capacity for embryonic cells to differentiate relies on a large-scale reprogramming of the oocyte and sperm nucleus into a transient totipotent state. In zebrafish, this reprogramming step is achieved...
4.
Gunter H, Youlten S, Reis A, McCubbin T, Madala B, Wong T, et al.
Nat Commun . 2024 Mar; 15(1):2480. PMID: 38509097
The expression of genes encompasses their transcription into mRNA followed by translation into protein. In recent years, next-generation sequencing and mass spectrometry methods have profiled DNA, RNA and protein abundance...
5.
Yam A, Bailey J, Lin F, Jakovija A, Youlten S, Counoupas C, et al.
Cancer Res . 2023 Feb; 83(8):1315-1328. PMID: 36787115
Significance: Intratumoral injection of microbial bioparticles stimulates neutrophil antitumor functions, suggesting pathways for optimizing efficacy of microbial therapies and paving the way for their broader utilization in the clinic.
6.
Gunter H, Youlten S, Madala B, Reis A, Stevanovski I, Wong T, et al.
Nat Commun . 2022 Oct; 13(1):6437. PMID: 36307482
Library adaptors are short oligonucleotides that are attached to RNA and DNA samples in preparation for next-generation sequencing (NGS). Adaptors can also include additional functional elements, such as sample indexes...
7.
Amodio M, Youlten S, Venkat A, San Juan B, Chaffer C, Krishnaswamy S
Patterns (N Y) . 2022 Sep; 3(9):100577. PMID: 36124302
Exciting advances in technologies to measure biological systems are currently at the forefront of research. The ability to gather data along an increasing number of omic dimensions has created a...
8.
Bergen D, Tong Q, Shukla A, Newham E, Zethof J, Lundberg M, et al.
BMC Biol . 2022 Jan; 20(1):21. PMID: 35057801
Background: Scales are mineralised exoskeletal structures that are part of the dermal skeleton. Scales have been mostly lost during evolution of terrestrial vertebrates whilst bony fish have retained a mineralised...
9.
Butterfield N, Curry K, Steinberg J, Dewhurst H, Komla-Ebri D, Mannan N, et al.
Nat Commun . 2021 May; 12(1):3302. PMID: 34050183
No abstract available.
10.
Youlten S, Kemp J, Logan J, Ghirardello E, Sergio C, Dack M, et al.
Nat Commun . 2021 May; 12(1):2444. PMID: 33953184
Osteocytes are master regulators of the skeleton. We mapped the transcriptome of osteocytes from different skeletal sites, across age and sexes in mice to reveal genes and molecular programs that...