Pernille Keller
Overview
Explore the profile of Pernille Keller including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
1262
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Recent Articles
1.
Schultz H, Guo L, Keller P, Fleetwood A, Sun M, Guo W, et al.
Eur J Immunol
. 2016 Jan;
46(4):952-63.
PMID: 26786702
Osteoclast-associated receptor (OSCAR) is an activating receptor expressed by human myeloid cells. Collagen type I (ColI) and collagen type II (ColII) serve as ligands for OSCAR. OSCAR-collagen interaction stimulates RANK-dependent...
2.
Folkersen L, Biswas S, Frederiksen K, Keller P, Fox B, Fleckner J
Drug Discov Today
. 2015 Jun;
20(10):1176-81.
PMID: 26050580
Recent groundbreaking work in genetics has identified thousands of small-effect genetic variants throughout the genome that are associated with almost all major diseases. These genome-wide association studies (GWAS) are often...
3.
Schultz H, Nitze L, Zeuthen L, Keller P, Gruhler A, Pass J, et al.
J Immunol
. 2015 Mar;
194(7):3169-79.
PMID: 25725106
Osteoclast-associated receptor (OSCAR) is widely expressed on human myeloid cells. Collagen types (Col)I, II, and III have been described as OSCAR ligands, and ColII peptides can induce costimulatory signaling in...
4.
Keller P, Gburcik V, Petrovic N, Gallagher I, Nedergaard J, Cannon B, et al.
BMC Endocr Disord
. 2011 Mar;
11:7.
PMID: 21426570
Background: Adipose tissue abundance relies partly on the factors that regulate adipogenesis, i.e. proliferation and differentiation of adipocytes. While components of the transcriptional program that initiates adipogenesis is well-known, the...
5.
Keller P, Vollaard N, Gustafsson T, Gallagher I, Sundberg C, Rankinen T, et al.
J Appl Physiol (1985)
. 2010 Oct;
110(1):46-59.
PMID: 20930125
The molecular pathways that are activated and contribute to physiological remodeling of skeletal muscle in response to endurance exercise have not been fully characterized. We previously reported that ∼800 gene...
6.
Gallagher I, Scheele C, Keller P, Nielsen A, Remenyi J, Fischer C, et al.
Genome Med
. 2010 Apr;
2(2):9.
PMID: 20353613
Background: Skeletal muscle insulin resistance (IR) is considered a critical component of type II diabetes, yet to date IR has evaded characterization at the global gene expression level in humans....
7.
Timmons J, Knudsen S, Rankinen T, Koch L, Sarzynski M, Jensen T, et al.
J Appl Physiol (1985)
. 2010 Feb;
108(6):1487-96.
PMID: 20133430
A low maximal oxygen consumption (VO2max) is a strong risk factor for premature mortality. Supervised endurance exercise training increases VO2max with a very wide range of effectiveness in humans. Discovering...
8.
Fredriksson K, Tjader I, Keller P, Petrovic N, Ahlman B, Scheele C, et al.
PLoS One
. 2008 Nov;
3(11):e3686.
PMID: 18997871
Background: Septic patients treated in the intensive care unit (ICU) often develop multiple organ failure including persistent skeletal muscle dysfunction which results in the patient's protracted recovery process. We have...
9.
Fox K, Colton L, Erickson P, Friedman J, Cha H, Keller P, et al.
J Biol Chem
. 2008 Oct;
283(50):35096-105.
PMID: 18957421
Cyclin D1 expression is elevated and Wnt10b is repressed by cAMP during the first few hours of adipogenesis. cAMP-responsive element-binding protein (CREB) is a primary target for cAMP signaling, and...
10.
Walden T, Timmons J, Keller P, Nedergaard J, Cannon B
J Cell Physiol
. 2008 Oct;
218(2):444-9.
PMID: 18937285
MicroRNAs, a novel class of post-transcriptional gene regulators, have been demonstrated to be involved in several cellular processes regulating the expression of protein-coding genes. Here we examine murine white and...