Juan Hidalgo
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Explore the profile of Juan Hidalgo including associated specialties, affiliations and a list of published articles.
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111
Citations
4008
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Recent Articles
1.
Tchen J, Simon Q, Chapart L, Thaminy M, Vibhushan S, Saveanu L, et al.
Nat Commun
. 2024 Apr;
15(1):3389.
PMID: 38649353
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by anti-nuclear autoantibodies whose production is promoted by autoreactive T follicular helper (TFH) cells. During SLE pathogenesis, basophils accumulate in secondary...
2.
Aguilar K, Canal C, Comes G, Diaz-Clavero S, Llanos M, Quintana A, et al.
J Inflamm (Lond)
. 2024 Jan;
21(1):1.
PMID: 38212783
Background: Mitochondrial diseases (MDs) are genetic disorders characterized by dysfunctions in mitochondria. Clinical data suggest that additional factors, beyond genetics, contribute to the onset and progression of this group of...
3.
Naon D, Hernandez-Alvarez M, Shinjo S, Wieczor M, Ivanova S, Martins de Brito O, et al.
Science
. 2023 Jun;
380(6651):eadh9351.
PMID: 37347868
In eukaryotic cells, different organelles interact at membrane contact sites stabilized by tethers. Mitochondrial mitofusin 2 (MFN2) acts as a membrane tether that interacts with an unknown partner on the...
4.
Aguilar K, Comes G, Canal C, Quintana A, Sanz E, Hidalgo J
Glia
. 2022 Jun;
70(11):2032-2044.
PMID: 35770802
Leigh syndrome is a mitochondrial disease characterized by neurodegeneration, neuroinflammation, and early death. Mice lacking NDUFS4, a mitochondrial complex I subunit (Ndufs4 KO mice), have been established as a good...
5.
Rohde D, Vandoorne K, Lee I, Grune J, Zhang S, McAlpine C, et al.
Nat Cardiovasc Res
. 2022 Jun;
1(1):28-44.
PMID: 35747128
Abnormal hematopoiesis advances cardiovascular disease by generating excess inflammatory leukocytes that attack the arteries and the heart. The bone marrow niche regulates hematopoietic stem cell proliferation and hence the systemic...
6.
Linge I, Tsareva A, Kondratieva E, Dyatlov A, Hidalgo J, Zvartsev R, et al.
Front Immunol
. 2022 Feb;
13:750068.
PMID: 35154093
The role of B cells migrating to the lung and forming follicles during tuberculosis (TB) inflammation is still the subject of debate. In addition to their antibody production and antigen-presenting...
7.
Gerosa R, Boettcher S, Kovtonyuk L, Hausmann A, Hardt W, Hidalgo J, et al.
Blood Adv
. 2021 Sep;
5(23):5002-5015.
PMID: 34581809
Hematopoiesis is maintained by hematopoietic stem and progenitor cells that are located in the bone marrow (BM) where they are embedded within a complex supportive microenvironment consisting of a multitude...
8.
Ait Ahmed Y, Fu Y, Rodrigues R, He Y, Guan Y, Guillot A, et al.
Cell Mol Immunol
. 2021 Jul;
18(9):2165-2176.
PMID: 34282300
Kupffer cells (KCs), which are liver-resident macrophages, originate from the fetal yolk sac and represent one of the largest macrophage populations in the body. However, the current data on the...
9.
Klawonn A, Fritz M, Castany S, Pignatelli M, Canal C, Simila F, et al.
Immunity
. 2021 Jan;
54(2):225-234.e6.
PMID: 33476547
Microglia are activated in many neurological diseases and have been suggested to play an important role in the development of affective disorders including major depression. To investigate how microglial signaling...
10.
Sanchis P, Fernandez-Gayol O, Comes G, Aguilar K, Escrig A, Giralt M, et al.
J Neuroinflammation
. 2020 Oct;
17(1):304.
PMID: 33059703
Background: Interleukin-6 (IL-6) is a pleiotropic cytokine that controls numerous physiological processes both in basal and neuroinflammatory conditions, including the inflammatory response to experimental autoimmune encephalomyelitis (EAE). IL-6 is produced...