Pavel Martasek
Overview
Explore the profile of Pavel Martasek including associated specialties, affiliations and a list of published articles.
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150
Citations
1850
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Recent Articles
1.
Skalickova M, Hadrava Vanova K, Uher O, Leischner Fialova J, Petrlakova K, Masarik M, et al.
Front Immunol
. 2025 Jan;
15:1479483.
PMID: 39850897
Despite enormous progress, advanced cancers are still one of the most serious medical problems in current society. Although various agents and therapeutic strategies with anticancer activity are known and used,...
2.
Vesela K, Kejik Z, Masarik M, Babula P, Dytrych P, Martasek P, et al.
ACS Pharmacol Transl Sci
. 2024 Nov;
7(11):3394-3418.
PMID: 39539276
Head and neck cancers (HNC) are aggressive, difficult-to-treat tumors that can be caused by genetic factors but mainly by lifestyle or infection caused by the human papillomavirus. As the sixth...
3.
Sabit H, Abdel-Ghany S, Abdallah M, Abul-Maaty O, Khoder A, Shoman N, et al.
Inflammopharmacology
. 2024 Oct;
32(6):3631-3652.
PMID: 39406981
As of the 7 of July 2024, 775,754,322 confirmed cases of COVID-19, including 7,053,902 deaths worldwide, had been reported to the WHO (World Health Organization). Nevertheless, untill the 15 of...
4.
Brogyanyi T, Kejik Z, Vesela K, Dytrych P, Hoskovec D, Masarik M, et al.
Biomed Pharmacother
. 2024 Sep;
179:117407.
PMID: 39265234
Mitochondrial autophagy (mitophagy) is very important process for the maintenance of cellular homeostasis, functionality and survival. Its dysregulation is associated with high risk and progression numerous serious diseases (e.g., oncological,...
5.
Kejik Z, Hajduch J, Abramenko N, Vellieux F, Vesela K, Leischner Fialova J, et al.
Commun Chem
. 2024 Aug;
7(1):180.
PMID: 39138299
Mitochondrial dysregulation plays a significant role in the carcinogenesis. On the other hand, its destabilization strongly represses the viability and metastatic potential of cancer cells. Photodynamic and photothermal therapies (PDT...
6.
Abramenko N, Vellieux F, Vesela K, Kejik Z, Hajduch J, Masarik M, et al.
Sci Rep
. 2024 Feb;
14(1):3043.
PMID: 38321096
Immune checkpoints regulate the immune system response. Recent studies suggest that flavonoids, known as phytoestrogens, may inhibit the PD-1/PD-L1 axis. We explored the potential of estrogens and 17 Selective Estrogen...
7.
Vozniuk O, Kejik Z, Vesela K, Skalickova M, Novotny P, Hromadka R, et al.
ChemistryOpen
. 2023 Nov;
13(3):e202300147.
PMID: 37955865
A simple, sensitive and quick HPLC method was developed for the determination of ketoprofen in cell culture media (EMEM, DMEM, RPMI). Separation was performed using a gradient on the C18...
8.
Kejik Z, Koubkova N, Krcova L, Sykora D, Abramenko N, Vesela K, et al.
Bioorg Chem
. 2023 Sep;
141:106816.
PMID: 37716274
Pentamethinium indolium salts are promising fluorescence probes and anticancer agents with high mitochondrial selectivity. We synthesized two indolium pentamethinium salts: a cyclic form with quinoxaline directly incorporated in the pentamethinium...
9.
Kaplanek R, Kejik Z, Hajduch J, Vesela K, Kucnirova K, Skalickova M, et al.
Biomed Pharmacother
. 2023 Aug;
166:115324.
PMID: 37598475
TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene expression. Dysregulation of their activity is associated with many serious pathogenic states such as oncological diseases. Regulation...
10.
Dytrych P, Kejik Z, Hajduch J, Kaplanek R, Vesela K, Kucnirova K, et al.
Biomed Pharmacother
. 2023 May;
163:114758.
PMID: 37141738
Treatment of metastatic cancer is one of the biggest challenges in anticancer therapy. Curcumin is interesting nature polyphenolic compound with unique biological and medicinal effects, including repression of metastases. High...