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Paul R Hess

Explore the profile of Paul R Hess including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 1316
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Recent Articles
1.
Stowe D, Held E, Cross E, Meritet D, Hess P, Ferris K, et al.
Vet Clin Pathol . 2024 Jul; 53(3):321-324. PMID: 39060224
During a 3-year time period, a 15-year-old male castrated Terrier mix (dog 1) and a 6-year-old female spayed Labrador Retriever (dog 2) presented to the North Carolina State Veterinary Hospital...
2.
Mason K, Sathe A, Hess P, Rong J, Wu C, Furth E, et al.
Genome Biol . 2024 Jan; 25(1):14. PMID: 38217002
Existing methods for analysis of spatial transcriptomic data focus on delineating the global gene expression variations of cell types across the tissue, rather than local gene expression changes driven by...
3.
Feng Y, Hess P, Tompkins S, Hildebrand W, Zhao S
iScience . 2023 Feb; 26(2):105996. PMID: 36798440
The major histocompatibility complex class I (MHC-I) genes are highly polymorphic. MHC-I genotyping is required for determining the peptide epitopes available to an individual's T-cell repertoire. Current genotyping software tools...
4.
Doka R, Suter S, Mastromauro M, Bennett A, Hess P
J Am Vet Med Assoc . 2022 Sep; 260(14):1827-1833. PMID: 36054007
Objective: To evaluate the efficacy of doxorubicin for treatment of histiocytic sarcoma (HS) in dogs, whether administered as the sole treatment or as an adjunct to surgery or radiation therapy....
5.
Holmes J, Scholl E, Dickey A, Hess P
Immunogenetics . 2021 Jun; 73(5):381-393. PMID: 34175985
Of the 12 full-length feline leukocyte antigen class I (FLAI) loci, 3 are presumed to be classical: FLAI-E, FLAI-H, and FLAI-K. As diversity is a class Ia hallmark, multi-allelism is...
6.
Nemec P, Holmes J, Hess P
HLA . 2021 Feb; 97(5):428-434. PMID: 33527745
Canine spontaneous cancers may offer greater fidelity than rodent models in advancing clinical immunotherapies. Boxers in particular are distinguished as study subjects by their popularity, and high incidence of human-relevant...
7.
Nemec P, Kapatos A, Holmes J, Stowe D, Hess P
Vet Comp Oncol . 2019 Mar; 17(3):317-328. PMID: 30854786
Cancer-testis antigens (CTAs) are a category of self proteins aberrantly expressed in diverse malignancies, mostly solid tumours, due to epigenetic de-repression. Normally expressed only in fetal or gametogenic tissues, CTAs...
8.
Hallman B, Hauck M, Williams L, Hess P, Suter S
J Vet Intern Med . 2019 Jan; 33(2):783-791. PMID: 30697816
Background: Doxorubicin (DOX) can cause cumulative cardiotoxicity in dogs, but the incidence of clinical cardiotoxicity in dogs receiving DOX has not been determined. Hypothesis/objectives: To determine if the duration of...
9.
Nemec P, Kapatos A, Holmes J, Hess P
HLA . 2018 Sep; 92(6):403-407. PMID: 30239163
Development of effective immunotherapy for chemoresistant malignancies can be advanced by studies in spontaneous cancer models, such as the dog. A crucial first step, T-cell epitope discovery, can be assisted...
10.
Dorman D, Foster M, Fernhoff K, Hess P
Vet Med (Auckl) . 2018 Jul; 8:69-76. PMID: 30050858
The scent detection prowess of dogs has prompted interest in their ability to detect cancer. The purpose of this study was to determine whether dogs could use olfactory cues to...