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Mark L Kahn

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Articles 121
Citations 4123
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Recent Articles
1.
Chen X, Tober J, Dominguez M, Tang A, Bockman J, Yang J, et al.
PLoS Biol . 2025 Jan; 23(1):e3003003. PMID: 39874373
Definitive hematopoietic stem and progenitor cells (HSPCs) arise from a small number of hemogenic endothelial cells (HECs) within the developing embryo. Understanding the origin and ontogeny of HSPCs is of...
2.
Gao S, Thillaikumaran T, Dominguez M, Giang W, Hayes K, Chen X, et al.
bioRxiv . 2024 Sep; PMID: 39345443
Normal placental development and angiogenesis are crucial for fetal growth and maternal health during pregnancy. However, molecular regulation of placental angiogenesis has been difficult to study due to a lack...
3.
Hogan B, Kahn M, Harvey N
Nat Cardiovasc Res . 2024 Aug; 2(3):193-195. PMID: 39195998
No abstract available.
4.
Ren J, Cui Z, Jiang C, Wang L, Guan Y, Ren Y, et al.
Am J Hum Genet . 2024 Jun; 111(7):1370-1382. PMID: 38917801
Extra-axial cavernous hemangiomas (ECHs) are complex vascular lesions mainly found in the spine and cavernous sinus. Their removal poses significant risk due to their vascularity and diffuse nature, and their...
5.
Yuki K, Vallon M, Ding J, Rada C, Tang A, Vilches-Moure J, et al.
Development . 2024 Apr; 151(11). PMID: 38682276
The GPR124/RECK/WNT7 pathway is an essential regulator of CNS angiogenesis and blood-brain barrier (BBB) function. GPR124, a brain endothelial adhesion seven-pass transmembrane protein, associates with RECK, which binds and stabilizes...
6.
Kahn M
JACC Basic Transl Sci . 2024 Mar; 9(2):220-222. PMID: 38510721
No abstract available.
7.
Li Y, Girard R, Srinath A, Vera Cruz D, Ciszewski C, Chen C, et al.
Cell Commun Signal . 2024 Jan; 22(1):23. PMID: 38195510
Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution...
8.
Ocskay Z, Balint L, Christ C, Kahn M, Jakus Z
Biomed Pharmacother . 2023 Dec; 170:116032. PMID: 38141283
Recent studies have described the importance of lymphatics in numerous organ-specific physiological and pathological processes. The role of meningeal lymphatics in various neurological and cerebrovascular diseases has been suggested. It...
9.
Gao S, Tang A, Wang M, Buchholz D, Imbiakha B, Yang J, et al.
Front Cardiovasc Med . 2023 Oct; 10:1266276. PMID: 37823176
Endothelial damage and vascular pathology have been recognized as major features of COVID-19 since the beginning of the pandemic. Two main theories regarding how severe acute respiratory syndrome coronavirus 2...
10.
Li L, Ren A, Gao S, Su Y, Yang J, Bockman J, et al.
Stroke . 2023 Sep; 54(11):2906-2917. PMID: 37746705
Background: Cerebral cavernous malformations (CCMs) are vascular malformations that frequently cause stroke. CCMs arise due to loss of function in one of the genes that encode the CCM complex, a...