Paul R Hess
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Explore the profile of Paul R Hess including associated specialties, affiliations and a list of published articles.
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1316
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Recent Articles
11.
Aynardi J, Manur R, Hess P, Chekol S, Morrissette J, Babushok D, et al.
Br J Haematol
. 2018 May;
182(1):78-85.
PMID: 29767839
The JAK2 V617F mutation is characteristic of most Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) and occurs rarely in de novo acute myeloid leukaemia (AML). We sought to characterize AMLs that harbour...
12.
Ross P, Nemec P, Kapatos A, Miller K, Holmes J, Suter S, et al.
Vet Immunol Immunopathol
. 2018 Feb;
197:76-86.
PMID: 29475511
Ideally, CD8+ T-cell responses against virally infected or malignant cells are defined at the level of the specific peptide and restricting MHC class I element, a determination not yet made...
13.
Leitman E, Palmer C, Buus S, Chen F, Riddell L, Sims S, et al.
PLoS One
. 2017 Oct;
12(10):e0184496.
PMID: 29020090
Antigen-specific T-cells are highly variable, spanning potent antiviral efficacy and damaging auto-reactivity. In virus infections, identifying the most efficacious responses is critical to vaccine design. However, current methods depend on...
14.
Sweet D, Jimenez J, Chang J, Hess P, Mericko-Ishizuka P, Fu J, et al.
J Clin Invest
. 2015 Jul;
125(8):2995-3007.
PMID: 26214523
Fluid shear forces have established roles in blood vascular development and function, but whether such forces similarly influence the low-flow lymphatic system is unknown. It has been difficult to test...
15.
Jakus Z, Gleghorn J, Enis D, Sen A, Chia S, Liu X, et al.
J Exp Med
. 2014 Apr;
211(5):815-26.
PMID: 24733830
Mammals must inflate their lungs and breathe within minutes of birth to survive. A key regulator of neonatal lung inflation is pulmonary surfactant, a lipoprotein complex which increases lung compliance...
16.
Boulaftali Y, Hess P, Kahn M, Bergmeier W
Circ Res
. 2014 Mar;
114(7):1174-84.
PMID: 24677237
Platelets are well-known for their critical role in hemostasis, that is, the prevention of blood loss at sites of mechanical vessel injury. Inappropriate platelet activation and adhesion, however, can lead...
17.
Hess P, Rawnsley D, Jakus Z, Yang Y, Sweet D, Fu J, et al.
J Clin Invest
. 2013 Dec;
124(1):273-84.
PMID: 24292710
Mammals transport blood through a high-pressure, closed vascular network and lymph through a low-pressure, open vascular network. These vascular networks connect at the lymphovenous (LV) junction, where lymph drains into...
18.
Hess S, Young E, Miller K, Vincent B, Buntzman A, Collins E, et al.
Transpl Immunol
. 2013 Oct;
29(1-4):138-45.
PMID: 24161680
Alloreactive T-cell responses directed against minor histocompatibility (H) antigens, which arise from diverse genetic disparities between donor and recipient outside the MHC, are an important cause of rejection of MHC-matched...
19.
Herzog B, Fu J, Wilson S, Hess P, Sen A, McDaniel J, et al.
Nature
. 2013 Sep;
502(7469):105-9.
PMID: 23995678
Circulating lymphocytes continuously enter lymph nodes for immune surveillance through specialized blood vessels named high endothelial venules, a process that increases markedly during immune responses. How high endothelial venules (HEVs)...
20.
Gojanovich G, Ross P, Holmer S, Holmes J, Hess P
Dev Comp Immunol
. 2013 Jul;
41(4):578-86.
PMID: 23892057
The function of the transporters associated with antigen processing (TAP) complex is to shuttle antigenic peptides from the cytosol to the endoplasmic reticulum to load MHC class I molecules for...