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Pascal F Durrenberger

Explore the profile of Pascal F Durrenberger including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 899
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Recent Articles
1.
Orr J, Laali A, Durrenberger P, Lazarus K, El Mdawar M, Janes S, et al.
Am J Physiol Lung Cell Mol Physiol . 2024 Aug; 327(4):L587-L599. PMID: 39137525
Basal cells are adult stem cells in the airway epithelium and regenerate differentiated cell populations, including the mucosecretory and ciliated cells that enact mucociliary clearance. Human basal cells can proliferate...
2.
Jochems S, de Ruiter K, Solorzano C, Voskamp A, Mitsi E, Nikolaou E, et al.
J Clin Invest . 2022 Jun; 132(11). PMID: 35642639
No abstract available.
3.
Pennycuick A, Teixeira V, AbdulJabbar K, Raza S, Lund T, Akarca A, et al.
Cancer Discov . 2020 Jul; 10(10):1489-1499. PMID: 32690541
Before squamous cell lung cancer develops, precancerous lesions can be found in the airways. From longitudinal monitoring, we know that only half of such lesions become cancer, whereas a third...
4.
Jochems S, de Ruiter K, Solorzano C, Voskamp A, Mitsi E, Nikolaou E, et al.
J Clin Invest . 2019 Jul; 129(10):4523-4538. PMID: 31361601
Streptococcus pneumoniae (Spn) is a common cause of respiratory infection, but also frequently colonizes the nasopharynx in the absence of disease. We used mass cytometry to study immune cells from...
5.
Selvarajah B, Azuelos I, Plate M, Guillotin D, Forty E, Contento G, et al.
Sci Signal . 2019 May; 12(582). PMID: 31113850
The differentiation of fibroblasts into a transient population of highly activated, extracellular matrix (ECM)-producing myofibroblasts at sites of tissue injury is critical for normal tissue repair. Excessive myofibroblast accumulation and...
6.
Teixeira V, Pipinikas C, Pennycuick A, Lee-Six H, Chandrasekharan D, Beane J, et al.
Nat Med . 2019 Jan; 25(3):517-525. PMID: 30664780
The molecular alterations that occur in cells before cancer is manifest are largely uncharted. Lung carcinoma in situ (CIS) lesions are the pre-invasive precursor to squamous cell carcinoma. Although microscopically...
7.
Bartoletti-Stella A, Corrado P, Mometto N, Baiardi S, Durrenberger P, Arzberger T, et al.
Mol Neurobiol . 2018 Nov; 56(7):5009-5024. PMID: 30446946
Functional genomics applied to the study of RNA expression profiles identified several abnormal molecular processes in experimental prion disease. However, only a few similar studies have been carried out to...
8.
Mercer P, Woodcock H, Eley J, Plate M, Sulikowski M, Durrenberger P, et al.
Thorax . 2016 Apr; 71(8):701-11. PMID: 27103349
Rationale: Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal of all fibrotic conditions with no curative therapies. Common pathomechanisms between IPF and cancer are increasingly recognised, including...
9.
Janczar K, Su Z, Raccagni I, Anfosso A, Kelly C, Durrenberger P, et al.
Biochem Soc Trans . 2015 Nov; 43(4):579-85. PMID: 26551696
The 18-kDa mitochondrial translocator protein (TSPO) is known to be highly expressed in several types of cancer, including gliomas, whereas expression in normal brain is low. TSPO functions in glioma...
10.
Holloway P, Durrenberger P, Trutschl M, Cvek U, Cooper D, Orr A, et al.
Arterioscler Thromb Vasc Biol . 2015 Jun; 35(9):1936-44. PMID: 26112010
Objective: Neutrophil recruitment is a key process in the pathogenesis of stroke, and may provide a valuable therapeutic target. Targeting the melanocortin (MC) receptors has previously shown to inhibit leukocyte...