Pascal F Durrenberger
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Explore the profile of Pascal F Durrenberger including associated specialties, affiliations and a list of published articles.
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24
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899
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Recent Articles
11.
Hurley M, Durrenberger P, Gentleman S, Walls A, Dexter D
J Mol Neurosci
. 2015 May;
57(1):48-62.
PMID: 25982926
Neuroinflammation is thought to contribute to cell death in neurodegenerative disorders, but the factors involved in the inflammatory process are not completely understood. Proteinase-activated receptor-2 (PAR2) expression in brain is...
12.
Su Z, Roncaroli F, Durrenberger P, Coope D, Karabatsou K, Hinz R, et al.
J Nucl Med
. 2015 Feb;
56(4):512-7.
PMID: 25722450
Unlabelled: The 18-kDa mitochondrial translocator protein (TSPO) is upregulated in high-grade astrocytomas and can be imaged by PET using the selective radiotracer (11)C-(R)PK11195. We investigated (11)C-(R)PK11195 binding in human gliomas...
13.
Durrenberger P, Fernando F, Kashefi S, Bonnert T, Seilhean D, Nait-Oumesmar B, et al.
J Neural Transm (Vienna)
. 2014 Aug;
122(7):1055-68.
PMID: 25119539
Neurodegenerative diseases of the central nervous system are characterized by pathogenetic cellular and molecular changes in specific areas of the brain that lead to the dysfunction and/or loss of explicit...
14.
Gardner C, Magliozzi R, Durrenberger P, Howell O, Rundle J, Reynolds R
Brain
. 2013 Nov;
136(Pt 12):3596-608.
PMID: 24176976
A substantial proportion of cases with secondary progressive multiple sclerosis have extensive inflammation in the leptomeninges that is associated with increased subpial demyelination, neuronal loss and an exacerbated disease course....
15.
Swingland J, Durrenberger P, Reynolds R, Dexter D, Pombo A, Deprez M, et al.
Front Neurosci
. 2012 Nov;
6:161.
PMID: 23162423
Background: Neurodegenerative diseases are characterized by key features such as loss of neurons, astrocytosis, and microglial activation/proliferation. These changes cause differences in the density of cell types between control and...
16.
Durrenberger P, Webb L, Sim M, Nicholas R, Altmann D, Boyton R
Immunology
. 2012 Oct;
137(4):317-25.
PMID: 23039207
The molecular mechanisms underpinning central nervous system damage in multiple sclerosis (MS) are complex and it is widely accepted that there is an autoimmune component. Both adaptive and innate immune...
17.
Durrenberger P, Fernando F, Magliozzi R, Kashefi S, Bonnert T, Ferrer I, et al.
Acta Neuropathol
. 2012 Aug;
124(6):893-903.
PMID: 22864814
The use of an appropriate reference gene to ensure accurate normalisation is crucial for the correct quantification of gene expression using qPCR assays and RNA arrays. The main criterion for...
18.
Durrenberger P, Grunblatt E, Fernando F, Monoranu C, Evans J, Riederer P, et al.
Parkinsons Dis
. 2012 May;
2012:214714.
PMID: 22548201
The aetiology of Parkinson's disease (PD) is yet to be fully understood but it is becoming more and more evident that neuronal cell death may be multifactorial in essence. The...
19.
Schmitt A, Leonardi-Essmann F, Durrenberger P, Wichert S, Spanagel R, Arzberger T, et al.
Eur Arch Psychiatry Clin Neurosci
. 2012 Mar;
262(7):565-77.
PMID: 22441714
Inaccurate wiring and synaptic pathology appear to be major hallmarks of schizophrenia. A variety of gene products involved in synaptic neurotransmission and receptor signaling are differentially expressed in brains of...
20.
Durrenberger P, Ettorre A, Kamel F, Webb L, Sim M, Nicholas R, et al.
J Neuroinflammation
. 2012 Jan;
9:1.
PMID: 22212381
Background: Pathogenic or regulatory effects of natural killer (NK) cells are implicated in many autoimmune diseases, but evidence in multiple sclerosis (MS) and its murine models remains equivocal. In an...