David T Dexter
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Explore the profile of David T Dexter including associated specialties, affiliations and a list of published articles.
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69
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2873
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Recent Articles
1.
Mancini M, Hausdorff J, Pelosin E, Bonato P, Camicioli R, Ellis T, et al.
J Parkinsons Dis
. 2025 Feb;
:1877718X241305626.
PMID: 40007168
Background: Research over the past twenty years has shown that gait outcomes have a high sensitivity for diagnosing Parkinson's disease (PD), for detecting the effects of interventions, and for monitoring...
2.
Khanna A, Adams J, Antoniades C, Bloem B, Carroll C, Cedarbaum J, et al.
NPJ Parkinsons Dis
. 2024 Nov;
10(1):225.
PMID: 39567515
Parkinson's Disease is a progressive neurodegenerative disorder afflicting almost 12 million people. Increased understanding of its complex and heterogenous disease pathology, etiology and symptom manifestations has resulted in the need...
3.
Kopil C, Asis A, Campbell C, Chowdhury S, Dexter D, Fargo K, et al.
J Parkinsons Dis
. 2024 Aug;
14(6):1105-1114.
PMID: 39121136
Parkinson's disease (PD) and dementia with Lewy bodies (DLB) share underlying neuropathology. Despite overlapping biology, therapeutic development has been approached separately for these clinical syndromes and there remains no treatment...
4.
Wyse R, Isaacs T, Barker R, Cookson M, Dawson T, Devos D, et al.
J Parkinsons Dis
. 2024 Apr;
14(4):657-666.
PMID: 38578902
In 2011, the UK medical research charity Cure Parkinson's set up the international Linked Clinical Trials (iLCT) committee to help expedite the clinical testing of potentially disease modifying therapies for...
5.
Al-Zaid F, Hurley M, Dexter D, Gillies G
NPJ Parkinsons Dis
. 2023 Jul;
9(1):119.
PMID: 37500636
Parkinson's disease (PD) is almost twice as prevalent in men, which has largely been attributed to neuroprotective effect of oestradiol in women. RORA (retinoic acid receptor-related orphan receptor alpha) regulates...
6.
Devos D, Labreuche J, Rascol O, Corvol J, Duhamel A, Guyon Delannoy P, et al.
N Engl J Med
. 2022 Nov;
387(22):2045-2055.
PMID: 36449420
Background: Iron content is increased in the substantia nigra of persons with Parkinson's disease and may contribute to the pathophysiology of the disorder. Early research suggests that the iron chelator...
7.
Ward R, Dexter D, Crichton R
Int J Mol Sci
. 2022 Jul;
23(13).
PMID: 35806270
Disturbance of the brain homeostasis, either directly via the formation of abnormal proteins or cerebral hypo-perfusion, or indirectly via peripheral inflammation, will activate microglia to synthesise a variety of pro-inflammatory...
8.
Coetzee T, Price Ball M, Boutin M, Bronson A, Dexter D, English R, et al.
J Particip Med
. 2021 Jul;
13(2):e31371.
PMID: 34255670
[This corrects the article DOI: 10.2196/23011.].
9.
Ward R, Dexter D, Martin-Bastida A, Crichton R
Int J Mol Sci
. 2021 Apr;
22(7).
PMID: 33805195
Iron loading in some brain regions occurs in Parkinson's Disease (PD), and it has been considered that its removal by iron chelators could be an appropriate therapeutic approach. Since neuroinflammation...
10.
Coetzee T, Price Ball M, Boutin M, Bronson A, Dexter D, English R, et al.
J Particip Med
. 2021 Mar;
13(1):e23011.
PMID: 33779573
Sharing clinical trial data can provide value to research participants and communities by accelerating the development of new knowledge and therapies as investigators merge data sets to conduct new analyses,...