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Osman Cen

Explore the profile of Osman Cen including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 366
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Recent Articles
1.
Varisli L, Tolan V, Cen J, Vlahopoulos S, Cen O
Oncol Res . 2023 Jun; 30(3):137-155. PMID: 37305018
Prostate cancer is one of the most often diagnosed malignancies in males and its prevalence is rising in both developed and developing countries. Androgen deprivation therapy has been used as...
2.
Sarohan A, Edipsoy S, Ozkurt Z, Ozlu C, Demir A, Cen O
Adv Exp Med Biol . 2023 May; 1436:153-166. PMID: 37253944
Mucormycosis is a rare but serious opportunistic fungal disease characterized by rhino-orbito-cerebral and pulmonary involvement. It is mainly seen in people with secondary immunosuppression, isolated vitamin A deficiency, measles, and...
3.
Sarohan A, Akelma H, Arac E, Aslan O, Cen O
Clin Nutr Open Sci . 2022 Jun; 43:85-94. PMID: 35664529
Background And Aims: COVID-19 has been a devastating pandemic. There are indications that vitamin A is depleted during infections. Vitamin A is important in development and immune homeostasis. It has...
4.
Sarohan A, Kizil M, Inkaya A, Mahmud S, Akram M, Cen O
Cell Signal . 2021 Aug; 87:110121. PMID: 34438017
The SARS-CoV-2 virus has caused a worldwide COVID-19 pandemic. In less than a year and a half, more than 200 million people have been infected and more than four million...
5.
Varisli L, Cen O, Vlahopoulos S
Immunology . 2019 Nov; 159(3):257-278. PMID: 31782148
Chloroquines are 4-aminoquinoline-based drugs mainly used to treat malaria. At pharmacological concentrations, they have significant effects on tissue homeostasis, targeting diverse signaling pathways in mammalian cells. A key target pathway...
6.
Cen O, Kannan K, Sappal J, Yu J, Zhang M, Arikan M, et al.
mSphere . 2018 Aug; 3(4). PMID: 30135222
Epstein-Barr virus (EBV) is associated with several B and epithelial cell cancers. EBV-encoded latent membrane protein 2A (LMP2A) contributes to cellular transformation by mimicking B cell receptor signaling. LMP2A/MYC double...
7.
Rink J, Yang S, Cen O, Taxter T, McMahon K, Misener S, et al.
Mol Pharm . 2017 Sep; 14(11):4042-4051. PMID: 28933554
Cancer cells have altered metabolism and, in some cases, an increased demand for cholesterol. It is important to identify novel, rational treatments based on biology, and cellular cholesterol metabolism as...
8.
Yigit B, Halibozek P, Chen S, OKeeffe M, Arnason J, Avigan D, et al.
Oncotarget . 2016 Mar; 7(18):26346-60. PMID: 27029059
The signaling lymphocyte activation molecule family [SLAMF] of cell surface receptors partakes in both the development of several immunocyte lineages and innate and adaptive immune responses in humans and mice....
9.
Moschovi M, Critselis E, Cen O, Adamaki M, Lambrou G, Chrousos G, et al.
Expert Rev Anticancer Ther . 2015 Nov; 15(12):1405-17. PMID: 26523494
Cancer treatment aims to exploit properties that define malignant cells. In recent years, it has become apparent that malignant cells often survive cancer treatment and ensuing cell stress by switching...
10.
Cen O, Longnecker R
Curr Top Microbiol Immunol . 2015 Oct; 391:151-80. PMID: 26428374
LMP2A is an EBV-encoded protein with three domains: (a) an N-terminal cytoplasmic domain, which has PY motifs that bind to WW domain-containing E3 ubiquitin ligases and an ITAM that binds...