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Richard Longnecker

Explore the profile of Richard Longnecker including associated specialties, affiliations and a list of published articles. Areas
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Articles 147
Citations 4072
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Recent Articles
1.
Zhen J, Chen J, Huang H, Liao S, Liu S, Yuan Y, et al.
J Virol . 2024 Oct; 98(11):e0119424. PMID: 39470208
Importance: Discovered in 1964, Epstein-Barr virus (EBV) is the first identified human oncogenic virus and the founding member of the gammaherpesvirus subfamily. In 1994, another cancer-causing virus was discovered in...
2.
Chan Y, Liu Z, Bastard P, Khobrekar N, Hutchison K, Yamazaki Y, et al.
Nature . 2024 Jul; 632(8024):390-400. PMID: 39048830
Most cases of herpes simplex virus 1 (HSV-1) encephalitis (HSE) remain unexplained. Here, we report on two unrelated people who had HSE as children and are homozygous for rare deleterious...
3.
Zhen J, Chen J, Huang H, Liao S, Liu S, Yuan Y, et al.
bioRxiv . 2024 Jul; PMID: 39026862
Importance: Discovered in 1964, Epstein-Barr virus (EBV) is the first identified human oncogenic virus and the founding member of the gammaherpesvirus subfamily. In 1994, another cancer-causing virus was discovered in...
4.
Quan J, Fan Q, Simons L, Smukowski S, Pegg C, Longnecker R, et al.
mBio . 2024 Jul; 15(8):e0144524. PMID: 38953638
Neurotropic alphaherpesviruses, including herpes simplex virus type 1 and pseudorabies virus, establish a lifelong presence within the peripheral nervous system of their mammalian hosts. Upon entering cells, two conserved tegument...
5.
Azcorra M, Gaertner Z, Davidson C, He Q, Kim H, Nagappan S, et al.
Nat Neurosci . 2023 Aug; 26(10):1762-1774. PMID: 37537242
Dopamine neurons are characterized by their response to unexpected rewards, but they also fire during movement and aversive stimuli. Dopamine neuron diversity has been observed based on molecular expression profiles;...
6.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mSphere . 2023 Jan; 8(2):e0003423. PMID: 36700653
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
7.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mBio . 2023 Jan; 14(1):e0018823. PMID: 36700642
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
8.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
J Virol . 2023 Jan; 97(2):e0008923. PMID: 36700640
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
9.
Fan Q, Hippler D, Yang Y, Longnecker R, Connolly S
mBio . 2023 Jan; 14(1):e0336822. PMID: 36629412
Enveloped virus entry requires fusion of the viral envelope with a host cell membrane. Herpes simplex virus 1 (HSV-1) entry is mediated by a set of glycoproteins that interact to...
10.
Ikeda M, Hayes C, Schaller S, Longnecker R
Blood Adv . 2022 May; 6(14):4283-4296. PMID: 35605249
MYC translocations in association with Epstein-Barr virus (EBV) infection are often observed in B-cell lymphomas. A subset of Burkitt lymphoma (BL) expresses EBV latent membrane proteins 1 and 2A (LMP1...