Nicolas Pietrancosta
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Explore the profile of Nicolas Pietrancosta including associated specialties, affiliations and a list of published articles.
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61
Citations
393
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Recent Articles
1.
Ayoub N, Upadhyay A, Tete A, Pietrancosta N, Munier-Lehmann H, OSullivan T
Eur J Med Chem
. 2024 Oct;
280:116920.
PMID: 39369481
Antimicrobial resistance poses a significant threat to global health, necessitating the development of novel therapeutic agents with unique mechanisms of action. Inosine 5'-monophosphate dehydrogenase (IMPDH), an essential enzyme in guanine...
2.
Favier M, Martin Garcia E, Icick R, de Almeida C, Jehl J, Desplanque M, et al.
Nat Commun
. 2024 Jul;
15(1):5691.
PMID: 38971801
Cholinergic striatal interneurons (ChIs) express the vesicular glutamate transporter 3 (VGLUT3) which allows them to regulate the striatal network with glutamate and acetylcholine (ACh). In addition, VGLUT3-dependent glutamate increases ACh...
3.
Henderson F, Dumas S, Gangarossa G, Bernard V, Pujol M, Poirel O, et al.
Cell Rep
. 2024 Jun;
43(7):114411.
PMID: 38944834
Exposure to stressors has profound effects on sleep that have been linked to serotonin (5-HT) neurons of the dorsal raphe nucleus (DR). However, the DR also comprises glutamatergic neurons expressing...
4.
Chen Y, Sewsurn S, Amand S, Kunz C, Pietrancosta N, Calabro K, et al.
ACS Chem Biol
. 2024 Apr;
19(4):886-895.
PMID: 38576157
Fungal paracyclophane-decahydrofluorene-containing natural products are complex polycyclic metabolites derived from similar hybrid PKS-NRPS pathways. Herein we studied the biosynthesis of pyrrocidines, one representative of this family, by gene inactivation in...
5.
Cois J, Bachollet S, Sanchez L, Pietrancosta N, Vialou V, Mallet J, et al.
Chemistry
. 2024 Apr;
30(32):e202400641.
PMID: 38573546
The combination of fluorogenic probes (fluorogens) and self-labeling protein tags represent a promising tool for imaging biological processes with high specificity but it requires the adequation between the fluorogen and...
6.
Ung D, Pietrancosta N, Badillo E, Raux B, Tapken D, Zlatanovic A, et al.
Mol Psychiatry
. 2024 Feb;
29(4):1205-1215.
PMID: 38418578
The ionotropic glutamate delta receptor GluD1, encoded by the GRID1 gene, is involved in synapse formation, function, and plasticity. GluD1 does not bind glutamate, but instead cerebellin and D-serine, which...
7.
Broch F, El Hajji L, Pietrancosta N, Gautier A
ACS Sens
. 2023 Oct;
8(10):3933-3942.
PMID: 37830919
Optical protein sensors that enable detection of relevant biomolecules of interest play central roles in biological research. Coupling fluorescent reporters with protein sensing units has enabled the development of a...
8.
de Almeida C, Chabbah N, Eyraud C, Fasano C, Bernard V, Pietrancosta N, et al.
eNeuro
. 2023 Jan;
10(2).
PMID: 36720646
Fear is an emotional mechanism that helps to cope with potential hazards. However, when fear is generalized, it becomes maladaptive and represents a core symptom of posttraumatic stress disorder (PTSD)....
9.
Nouri K, Pietrancosta N, Le Corre L, Dansette P, Mansuy D, Boucher J
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36498943
Cytochrome P450 2U1 (CYP2U1) identified from the human genome remains poorly known since few data are presently available on its physiological function(s) and substrate(s) specificity. CYP2U1 mutations are associated with...
10.
Cristofari P, Desplanque M, Poirel O, Hebert A, Dumas S, Herzog E, et al.
Front Mol Neurosci
. 2022 Sep;
15:991732.
PMID: 36176961
Striatal cholinergic interneurons (CINs) use acetylcholine (ACh) and glutamate (Glut) to regulate the striatal network since they express vesicular transporters for ACh (VAChT) and Glut (VGLUT3). However, whether ACh and...