Nicolas Pietrancosta
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Explore the profile of Nicolas Pietrancosta including associated specialties, affiliations and a list of published articles.
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61
Citations
393
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Recent Articles
11.
Bachollet S, Pietrancosta N, Mallet J, Dumat B
Chem Commun (Camb)
. 2022 May;
58(46):6594-6597.
PMID: 35593406
We introduce a strategy for the fluorogenic and genetic targeting of a calcium indicator by combining a protein fluorogen with the BAPTA sensing group. The resulting dual-input probe acts like...
12.
Bachollet S, Shpinov Y, Broch F, Benaissa H, Gautier A, Pietrancosta N, et al.
Org Biomol Chem
. 2022 Apr;
20(17):3619-3628.
PMID: 35420083
We report the development of HaloTag fluorogens based on dipolar flexible molecular rotor structures. By modulating the electron donating and withdrawing groups, we have tuned the absorption and emission wavelengths...
13.
Sitbon J, Nestvogel D, Kappeler C, Nicolas A, Maciuba S, Henrion A, et al.
Mol Psychiatry
. 2022 Feb;
27(2):1145-1157.
PMID: 35169262
Bipolar disorder is a severe and chronic psychiatric disease resulting from a combination of genetic and environmental risk factors. Here, we identified a significant higher mutation rate in a gene...
14.
Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging
Benaissa H, Ounoughi K, Aujard I, Fischer E, Goiame R, Nguyen J, et al.
Nat Commun
. 2021 Dec;
12(1):6989.
PMID: 34848727
Biocompatible fluorescent reporters with spectral properties spanning the entire visible spectrum are indispensable tools for imaging the biochemistry of living cells and organisms in real time. Here, we report the...
15.
Rebeillard F, De Gois S, Pietrancosta N, Mai T, Lai-Kuen R, Kieffer B, et al.
Cereb Cortex
. 2021 Jul;
32(3):479-489.
PMID: 34247243
GPR88 is an orphan G-protein-coupled receptor (GPCR) highly expressed in striatal medium spiny neurons (MSN), also found in cortical neurons at low level. In MSN, GPR88 has a canonical GPCR...
16.
Favier M, Pietrancosta N, El Mestikawy S, Gangarossa G
Trends Pharmacol Sci
. 2021 Mar;
42(6):475-490.
PMID: 33775453
Vesicular glutamate transporters (VGLUTs) were long thought to be specific markers of glutamatergic excitatory transmission. The discovery, two decades ago, of the atypical VGLUT3 has thoroughly modified this oversimplified view....
17.
Hayek S, Pietrancosta N, Alves de Sousa R, Barouki R, Herbeuval J, Vidalain P
Virologie (Montrouge)
. 2020 Oct;
22(1):27-40.
PMID: 33111666
Environmental pollution is of concern to civil society and as the problem intensifies, there is increasing pressure on politicians and polluters to assess and mitigate this risk. In addition, the...
18.
Hayek S, Pietrancosta N, Alves de Sousa R, Barouki R, Herbeuval J, Vidalain P
Virologie (Montrouge)
. 2020 Oct;
22(1):1-13.
PMID: 33111665
Environmental pollution is of concern to civil society and as the problem intensifies, there is increasing pressure on politicians and polluters to assess and mitigate this risk. In addition, the...
19.
Bachollet S, Addi C, Pietrancosta N, Mallet J, Dumat B
Chemistry
. 2020 Jul;
26(63):14467-14473.
PMID: 32691883
Fluorogenic probes are important tools to image proteins with high contrast and no wash protocols. In this work, we rationally designed and synthesized a small set of four protein fluorogens...
20.
Dubois L, Pietrancosta N, Cabaye A, Fanget I, Debacker C, Gilormini P, et al.
J Med Chem
. 2020 Jul;
63(15):8231-8249.
PMID: 32608236
Sialin, encoded by the gene, is a lysosomal sialic acid transporter defective in Salla disease, a rare inherited leukodystrophy. It also enables metabolic incorporation of exogenous sialic acids, leading to...