Nicholas W Gale
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Explore the profile of Nicholas W Gale including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
5265
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Recent Articles
1.
Nistala H, Dronzek J, Gonzaga-Jauregui C, Chim S, Rajamani S, Nuwayhid S, et al.
Hum Mol Genet
. 2020 Oct;
29(21):3516-3531.
PMID: 33105479
Neurodevelopmental disorder with microcephaly, hypotonia and variable brain anomalies (NMIHBA) is an autosomal recessive neurodevelopmental and neurodegenerative disorder characterized by global developmental delay and severe intellectual disability. Microcephaly, progressive cortical...
2.
Deckelbaum R, Lobov I, Cheung E, Halasz G, Rajamani S, Lerner J, et al.
Angiogenesis
. 2019 Nov;
23(2):179-192.
PMID: 31754927
Angiogenesis is largely driven by motile endothelial tip-cells capable of invading avascular tissue domains and enabling new vessel formation. Highly responsive to Vascular Endothelial Growth-Factor-A (VEGFA), endothelial tip-cells also suppress...
3.
Voronina V, Harris F, Schmahl J, Galligan C, Oristian D, Zamfirova R, et al.
Biol Reprod
. 2018 Oct;
100(3):686-696.
PMID: 30289441
The Adisintegrin and metalloprotease domain-containing (ADAM) family of proteins is involved in cell adhesion, migration, proteolysis, and signaling. Many ADAMs are required for reproduction; however, the role of Adam6 has...
4.
Takahashi K, Kim R, Lauhan C, Park Y, Nguyen N, Vestweber D, et al.
PLoS One
. 2017 May;
12(5):e0177192.
PMID: 28542220
Renal vascular development is a coordinated process that requires ordered endothelial cell proliferation, migration, intercellular adhesion, and morphogenesis. In recent decades, studies have defined the pivotal role of endothelial receptor...
5.
Johnson L, Banerji S, Lawrance W, Gileadi U, Prota G, Holder K, et al.
Nat Immunol
. 2017 May;
18(7):762-770.
PMID: 28504698
Trafficking of tissue dendritic cells (DCs) via lymph is critical for the generation of cellular immune responses in draining lymph nodes (LNs). In the current study we found that DCs...
6.
Das G, Yu Q, Hui R, Reuhl K, Gale N, Zhou R
Cell Biosci
. 2016 Aug;
6:48.
PMID: 27489614
Background: The Eph family of receptor tyrosine kinases plays important roles in neural development. Previous studies have implicated Eph receptors and their ligands, the ephrins, in neuronal migration, axon bundling...
7.
Mastaitis J, Eckersdorff M, Min S, Xin Y, Cavino K, Aglione J, et al.
Endocrinology
. 2015 Sep;
156(12):4502-10.
PMID: 26406932
Secreted frizzled-related protein 4 (SFRP4) is an extracellular regulator of the wingless-type mouse mammary tumor virus integration site family (WNT) pathway. SFRP4 has been implicated in adipocyte dysfunction, obesity, insulin...
8.
Mastaitis J, Min S, Elvert R, Kannt A, Xin Y, Ochoa F, et al.
Proc Natl Acad Sci U S A
. 2015 Jan;
112(6):1845-9.
PMID: 25624481
G protein-coupled receptor 17 (GPR17) was recently reported to be a Foxo1 target in agouti-related peptide (AGRP) neurons. Intracerebroventricular injection of GPR17 agonists induced food intake, whereas administration of an...
9.
Thomson B, Heinen S, Jeansson M, Ghosh A, Fatima A, Sung H, et al.
J Clin Invest
. 2014 Sep;
124(10):4320-4.
PMID: 25202984
Glaucoma is a leading cause of blindness, afflicting more than 60 million people worldwide. Increased intraocular pressure (IOP) due to impaired aqueous humor drainage is a major risk factor for...
10.
Wong M, Dazai J, Walls J, Gale N, Henkelman R
PLoS One
. 2013 Sep;
8(9):e73491.
PMID: 24023880
Optical projection tomography (OPT) is an imaging modality that has, in the last decade, answered numerous biological questions owing to its ability to view gene expression in 3 dimensions (3D)...