Nerissa T Williams
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Explore the profile of Nerissa T Williams including associated specialties, affiliations and a list of published articles.
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19
Citations
118
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Recent Articles
1.
Wu S, Sharpe J, Tolliver J, Groth A, Chen R, Guerra Garcia M, et al.
Neoplasia
. 2025 Mar;
62:101139.
PMID: 40056601
Diffuse midline gliomas (DMGs) are lethal brain tumors that arise in children and young adults, resulting in a median survival of less than two years. Genetically engineered mouse models (GEMMs)...
2.
Finkelstein S, Patel R, Deland K, Mercer J, Starr B, Zhu D, et al.
Radiat Res
. 2024 Sep;
202(5):734-744.
PMID: 39307527
The main deterrent to long-term space travel is the risk of Radiation Exposure Induced Death (REID). The National Aeronautics and Space Administration (NASA) has adopted Permissible Exposure Levels (PELs) to...
3.
Su C, Kent C, Pierpoint M, Floyd W, Luo L, Williams N, et al.
JCI Insight
. 2024 Aug;
9(14).
PMID: 39133651
Radiation therapy (RT) is frequently used to treat cancers, including soft-tissue sarcomas. Prior studies established that the toll-like receptor 9 (TLR9) agonist cytosine-phosphate-guanine oligodeoxynucleotide (CpG) enhances the response to RT...
4.
Patel R, Cooper D, Kadakia K, Allen A, Duan L, Luo L, et al.
Commun Biol
. 2024 May;
7(1):608.
PMID: 38769385
Diverse tumor metabolic phenotypes are influenced by the environment and genetic lesions. Whether these phenotypes extend to rhabdomyosarcoma (RMS) and how they might be leveraged to design new therapeutic approaches...
5.
Odhiambo D, Pittman A, Rickard A, Castillo R, Bassil A, Chen J, et al.
Int J Radiat Oncol Biol Phys
. 2023 Dec;
118(5):1315-1327.
PMID: 38104870
Purpose: Despite aggressive multimodal treatment that typically includes definitive or adjuvant radiation therapy (RT), locoregional recurrence rates approach 50% for patients with locally advanced human papillomavirus (HPV)-negative head and neck...
6.
Guo W, Hoque J, Garcia Garcia C, Spiller K, Leinroth A, Puviindran V, et al.
Sci Transl Med
. 2023 Nov;
15(724):eabo5217.
PMID: 38019933
Radiotherapy remains a common treatment modality for cancer despite skeletal complications. However, there are currently no effective treatments for radiation-induced bone loss, and the consequences of radiotherapy on skeletal progenitor...
7.
Tu K, Stewart C, Williams N, Ma Y, Luo L, Ghosh D, et al.
Radiat Res
. 2023 Nov;
200(6):587-592.
PMID: 37990957
Medulloblastoma is the most common malignant brain tumor of children. Although standard of care radiotherapy for pediatric medulloblastoma (PM) can lead to long-term remission or cure in many patients, it...
8.
Daniel A, Su C, Williams N, Li Z, Huang J, Lopez O, et al.
Cancer Res Commun
. 2023 Nov;
3(12):2455-2467.
PMID: 37982576
Significance: Strategies to prevent or mitigate acute radiation toxicities include pharmacologic inhibition of p53 and other cell death pathways. Our data show that temporarily reducing p53 during irradiation increases late...
9.
Mangoli A, Wu S, Liu H, Aksu M, Jain V, Foreman B, et al.
bioRxiv
. 2023 Oct;
PMID: 37904990
Diffuse midline gliomas (DMGs) are lethal brain tumors characterized by p53-inactivating mutations and oncohistone H3.3K27M mutations that rewire the cellular response to genotoxic stress, which presents therapeutic opportunities. We used...
10.
Rickard A, Mowery Y, Bassil A, Rouse D, Williams N, Charity T, et al.
Mol Imaging Biol
. 2023 Sep;
26(3):435-447.
PMID: 37721686
Purpose: Tumor hypoxia contributes to aggressive phenotypes and diminished therapeutic responses to radiation therapy (RT) with hypoxic tissue being 3-fold less radiosensitive than normoxic tissue. A major challenge in implementing...