Nerissa T Williams
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Explore the profile of Nerissa T Williams including associated specialties, affiliations and a list of published articles.
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19
Citations
118
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Recent Articles
11.
Floyd W, Pierpoint M, Su C, Patel R, Luo L, Deland K, et al.
J Clin Invest
. 2023 May;
133(13).
PMID: 37200088
ATRX is one of the most frequently altered genes in solid tumors, and mutation is especially frequent in soft tissue sarcomas. However, the role of ATRX in tumor development and...
12.
Weidenhammer L, Liu H, Luo L, Williams N, Deland K, Kirsch D, et al.
STAR Protoc
. 2023 Feb;
4(1):102094.
PMID: 36853662
Genetically engineered mice are commonly used to model brainstem gliomas in pre-clinical research. One technique for inducing primary tumors in these genetically engineered mice involves delivering viral vectors containing the...
13.
Patel R, Mowery Y, Qi Y, Bassil A, Holbrook M, Xu E, et al.
Mol Cancer Ther
. 2022 Sep;
22(1):112-122.
PMID: 36162051
This study aims to investigate whether adding neoadjuvant radiotherapy (RT), anti-programmed cell death protein-1 (PD-1) antibody (anti-PD-1), or RT + anti-PD-1 to surgical resection improves disease-free survival for mice with...
14.
Stewart C, Guerra-Garcia M, Luo L, Williams N, Ma Y, Regal J, et al.
Cancers (Basel)
. 2022 Sep;
14(18).
PMID: 36139666
Diffuse midline gliomas arise in the brainstem and other midline brain structures and cause a large proportion of childhood brain tumor deaths. Radiation therapy is the most effective treatment option,...
15.
Kuo H, Luo L, Ma Y, Williams N, Campos L, Attardi L, et al.
Radiat Res
. 2022 May;
198(2):145-153.
PMID: 35512345
Thoracic radiation therapy can cause endothelial injury in the heart, leading to cardiac dysfunction and heart failure. Although it has been demonstrated that the tumor suppressor p53 functions in endothelial...
16.
Johnson T, Bassil A, Williams N, Brundage S, Kent C, Palmer G, et al.
Phys Med Biol
. 2022 Jan;
67(4).
PMID: 35100573
. To develop and characterize novel methods of extreme spatially fractionated kV radiation therapy (including mini-GRID therapy) and to evaluate efficacy in the context of a pre-clinical mouse study.. Spatially...
17.
Deland K, Mercer J, Crabtree D, Guerra Garcia M, Reinsvold M, Campos L, et al.
Int J Radiat Oncol Biol Phys
. 2021 Oct;
112(3):771-779.
PMID: 34619331
Purpose: Diffuse intrinsic pontine gliomas (DIPGs) arise in the pons and are the leading cause of death from brain tumors in children. DIPGs are routinely treated with radiation therapy, which...
18.
Wisdom A, Mowery Y, Hong C, Himes J, Nabet B, Qin X, et al.
Nat Commun
. 2020 Dec;
11(1):6410.
PMID: 33335088
Immunotherapy fails to cure most cancer patients. Preclinical studies indicate that radiotherapy synergizes with immunotherapy, promoting radiation-induced antitumor immunity. Most preclinical immunotherapy studies utilize transplant tumor models, which overestimate patient...
19.
Deland K, Starr B, Mercer J, Byemerwa J, Crabtree D, Williams N, et al.
J Clin Invest
. 2020 Sep;
131(1).
PMID: 32990677
Diffuse intrinsic pontine glioma (DIPG) kills more children than any other type of brain tumor. Despite clinical trials testing many chemotherapeutic agents, palliative radiotherapy remains the standard treatment. Here, we...
20.
Huang J, Sachdeva M, Xu E, Robinson T, Luo L, Ma Y, et al.
Mol Cancer Res
. 2020 Jun;
18(10):1534-1544.
PMID: 32561656
Soft-tissue sarcomas (STS) are rare malignancies showing lineage differentiation toward diverse mesenchymal tissues. Half of all high-grade STSs develop lung metastasis with a median survival of 15 months. Here, we...