Rutulkumar Patel
Overview
Explore the profile of Rutulkumar Patel including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
439
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0
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Recent Articles
1.
Finkelstein S, Patel R, Deland K, Mercer J, Starr B, Zhu D, et al.
Radiat Res
. 2024 Sep;
202(5):734-744.
PMID: 39307527
The main deterrent to long-term space travel is the risk of Radiation Exposure Induced Death (REID). The National Aeronautics and Space Administration (NASA) has adopted Permissible Exposure Levels (PELs) to...
2.
Patel R, Cooper D, Kadakia K, Allen A, Duan L, Luo L, et al.
Commun Biol
. 2024 May;
7(1):608.
PMID: 38769385
Diverse tumor metabolic phenotypes are influenced by the environment and genetic lesions. Whether these phenotypes extend to rhabdomyosarcoma (RMS) and how they might be leveraged to design new therapeutic approaches...
3.
Finkelstein S, Patel R, Deland K, Mercer J, Starr B, Zhu D, et al.
bioRxiv
. 2023 Jun;
PMID: 37333373
The main deterrent to long-term space travel is the risk of Radiation Exposure Induced Death (REID). The National Aeronautics and Space Administration (NASA) has adopted Permissible Exposure Levels (PELs) to...
4.
Floyd W, Pierpoint M, Su C, Patel R, Luo L, Deland K, et al.
J Clin Invest
. 2023 May;
133(13).
PMID: 37200088
ATRX is one of the most frequently altered genes in solid tumors, and mutation is especially frequent in soft tissue sarcomas. However, the role of ATRX in tumor development and...
5.
Patel R, Mowery Y, Qi Y, Bassil A, Holbrook M, Xu E, et al.
Mol Cancer Ther
. 2022 Sep;
22(1):112-122.
PMID: 36162051
This study aims to investigate whether adding neoadjuvant radiotherapy (RT), anti-programmed cell death protein-1 (PD-1) antibody (anti-PD-1), or RT + anti-PD-1 to surgical resection improves disease-free survival for mice with...
6.
Holbrook M, Clark D, Patel R, Qi Y, Bassil A, Mowery Y, et al.
Tomography
. 2021 Aug;
7(3):358-372.
PMID: 34449750
We are developing imaging methods for a co-clinical trial investigating synergy between immunotherapy and radiotherapy. We perform longitudinal micro-computed tomography (micro-CT) of mice to detect lung metastasis after treatment. This...
7.
Schmidt D, Patel R, Kirsch D, Lewis C, Vander Heiden M, Locasale J
CA Cancer J Clin
. 2021 May;
71(4):333-358.
PMID: 33982817
Cancer has myriad effects on metabolism that include both rewiring of intracellular metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor microenvironment, and changes in normal...
8.
Tan S, Mahmud I, Fontanesi F, Puchowicz M, Neumann C, Griswold A, et al.
Cancer Discov
. 2021 Mar;
11(8):2072-2093.
PMID: 33757970
Clear cell renal cell carcinoma (ccRCC) is characterized by accumulation of neutral lipids and adipogenic transdifferentiation. We assessed adipokine expression in ccRCC and found that tumor tissues and patient plasma...
9.
Wisdom A, Mowery Y, Hong C, Himes J, Nabet B, Qin X, et al.
Nat Commun
. 2020 Dec;
11(1):6410.
PMID: 33335088
Immunotherapy fails to cure most cancer patients. Preclinical studies indicate that radiotherapy synergizes with immunotherapy, promoting radiation-induced antitumor immunity. Most preclinical immunotherapy studies utilize transplant tumor models, which overestimate patient...
10.
Patel R, Zhang L, Desai A, Hoenerhoff M, Kennedy L, Radivoyevitch T, et al.
Int J Radiat Oncol Biol Phys
. 2020 Jul;
108(4):1091-1102.
PMID: 32629081
Purpose: Humans are exposed to charged particles in different scenarios. The use of protons and high-linear energy transfer (LET) in cancer treatment is steadily growing. In outer space, astronauts will...