Neil A Mabbott
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Explore the profile of Neil A Mabbott including associated specialties, affiliations and a list of published articles.
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119
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2910
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Recent Articles
11.
Christodoulidou M, Mabbott N
Immunother Adv
. 2023 Oct;
3(1):ltad020.
PMID: 37886620
The Mpox virus (MPXV) is endemic in certain countries in Central and West Africa, where several mammalian species, especially rodents, are natural reservoirs. However, the MPXV can infect nonhuman primates...
12.
Quintana J, Sinton M, Chandrasegaran P, Lestari A, Heslop R, Cheaib B, et al.
Nat Commun
. 2023 Aug;
14(1):5279.
PMID: 37644007
African trypanosomes colonise the skin to ensure parasite transmission. However, how the skin responds to trypanosome infection remains unresolved. Here, we investigate the local immune response of the skin in...
13.
Herbst C, Bouteau A, Menyko E, Qin Z, Su Q, Buelvas D, et al.
bioRxiv
. 2023 Aug;
PMID: 37546718
Macrophages and dendritic cells (DCs) in peripheral tissue interact closely with their local microenvironment by scavenging protein and nucleic acids released by neighboring cells. Material transfer between cell types is...
14.
Chambers E, Vukmanovic-Stejic M, Shih B, Trahair H, Subramanian P, Devine O, et al.
Nat Aging
. 2023 Apr;
1(1):101-113.
PMID: 37118005
We have previously shown that healthy older adults exhibit reduced cutaneous immune responses during a varicella zoster virus (VZV) antigen challenge that correlated with a nonspecific inflammatory response to the...
15.
Nash T, Morris K, Mabbott N, Vervelde L
Vet Res
. 2023 Feb;
54(1):12.
PMID: 36793124
Enteroids are miniature self-organising three-dimensional (3D) tissue cultures which replicate much of the complexity of the intestinal epithelium. We recently developed an apical-out leukocyte-containing chicken enteroid model providing a novel...
16.
Chambers E, Vukmanovic-Stejic M, Turner C, Shih B, Trahair H, Pollara G, et al.
Immunother Adv
. 2022 Oct;
1(1):ltaa008.
PMID: 36284901
Introduction: Ageing is associated with increased number of infections, decreased vaccine efficacy and increased systemic inflammation termed inflammageing. These changes are reflected by reduced recall responses to varicella zoster virus...
17.
Quintana J, Chandrasegaran P, Sinton M, Briggs E, Otto T, Heslop R, et al.
Nat Commun
. 2022 Sep;
13(1):5752.
PMID: 36180478
Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasite Trypanosoma brucei and induces profound reactivity of glial cells and neuroinflammation when the parasites colonise the central nervous...
18.
Shih B, Brown S, Barrington J, Lefevre L, Mabbott N, Priller J, et al.
Glia
. 2022 Sep;
71(2):334-349.
PMID: 36120803
Microglia play key roles in brain homeostasis as well as responses to neurodegeneration and neuroinflammatory processes caused by physical disease and psychosocial stress. The pig is a physiologically relevant model...
19.
Pal R, Bradford B, Mabbott N
Front Cell Neurosci
. 2022 Jul;
16:918883.
PMID: 35875357
Prion diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy in cattle, and scrapie in sheep, are infectious and chronic neurodegenerative diseases to which there are no cures. Infection...
20.
Bradford B, McGuire L, Hume D, Pridans C, Mabbott N
Glia
. 2022 Jul;
70(11):2169-2187.
PMID: 35852018
Prion diseases are transmissible, neurodegenerative disorders associated with misfolding of the prion protein. Previous studies show that reduction of microglia accelerates central nervous system (CNS) prion disease and increases the...