Anuj Sehgal
Overview
Explore the profile of Anuj Sehgal including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
487
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0
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Recent Articles
1.
Carter-Cusack D, Huang S, Keshvari S, Patkar O, Sehgal A, Allavena R, et al.
PLoS Genet
. 2025 Jan;
21(1):e1011525.
PMID: 39869647
Adaptation to existence outside the womb is a key event in the life of a mammal. The absence of macrophages in rats with a homozygous mutation in the colony-stimulating factor...
2.
Batoon L, Keshvari S, Irvine K, Ho E, Caruso M, Patkar O, et al.
J Leukoc Biol
. 2024 Mar;
116(4):753-765.
PMID: 38526212
Macrophage and osteoclast proliferation, differentiation and survival are regulated by colony-stimulating factor 1 receptor (CSF1R) signaling. Osteopetrosis associated with Csf1 and Csf1r mutations has been attributed to the loss of...
3.
Muir R, Sehgal A, Tye-Din J, Daveson A
Med J Aust
. 2023 Sep;
219(8):371-373.
PMID: 37716708
No abstract available.
4.
Sehgal A, Carter-Cusack D, Keshvari S, Patkar O, Huang S, Summers K, et al.
Eur J Immunol
. 2023 Apr;
53(8):e2250312.
PMID: 37059596
Homozygous null mutation of the Csf1r gene (Csf1rko) in rats leads to the loss of most tissue macrophage populations and pleiotropic impacts on postnatal growth and organ maturation, leading to...
5.
Hume D, Batoon L, Sehgal A, Keshvari S, Irvine K
Curr Osteoporos Rep
. 2022 Oct;
20(6):516-531.
PMID: 36197652
Purpose Of Review: The purpose of the review is to summarize the expression and function of CSF1R and its ligands in bone homeostasis and constraints on therapeutic targeting of this...
6.
Stables J, Green E, Sehgal A, Patkar O, Keshvari S, Taylor I, et al.
Development
. 2022 Mar;
149(8).
PMID: 35333324
Amino acid substitutions in the kinase domain of the human CSF1R gene are associated with autosomal dominant adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP). To model the human...
7.
Millard S, Heng O, Opperman K, Sehgal A, Irvine K, Kaur S, et al.
Cell Rep
. 2021 Nov;
37(8):110058.
PMID: 34818538
Mouse hematopoietic tissues contain abundant tissue-resident macrophages that support immunity, hematopoiesis, and bone homeostasis. A systematic strategy to characterize macrophage subsets in mouse bone marrow (BM), spleen, and lymph node...
8.
Sehgal A, Irvine K, Hume D
Semin Immunol
. 2021 Nov;
54:101509.
PMID: 34742624
Macrophage colony-stimulating factor (CSF1) is the primary growth factor required for the control of monocyte and macrophage differentiation, survival, proliferation and renewal. Although the cDNAs encoding multiple isoforms of human...
9.
Keshvari S, Caruso M, Teakle N, Batoon L, Sehgal A, Patkar O, et al.
PLoS Genet
. 2021 Jun;
17(6):e1009605.
PMID: 34081701
Homozygous mutation of the Csf1r locus (Csf1rko) in mice, rats and humans leads to multiple postnatal developmental abnormalities. To enable analysis of the mechanisms underlying the phenotypic impacts of Csf1r...
10.
Hume D, Caruso M, Keshvari S, Patkar O, Sehgal A, Bush S, et al.
J Immunol
. 2021 May;
206(10):2251-2263.
PMID: 33965905
The laboratory rat continues to be the model of choice for many studies of physiology, behavior, and complex human diseases. Cells of the mononuclear phagocyte system (MPS; monocytes, macrophages, and...