Nathaniel M Green
Overview
Explore the profile of Nathaniel M Green including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
586
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Recent Articles
1.
Drummond R, Desai J, Ricotta E, Swamydas M, Deming C, Conlan S, et al.
Cell Host Microbe
. 2022 May;
30(7):1020-1033.e6.
PMID: 35568028
Antibiotics are a modifiable iatrogenic risk factor for the most common human nosocomial fungal infection, invasive candidiasis, yet the underlying mechanisms remain elusive. We found that antibiotics enhanced the susceptibility...
2.
Swamydas M, Gao J, Break T, Johnson M, Jaeger M, Rodriguez C, et al.
Sci Transl Med
. 2016 Jan;
8(322):322ra10.
PMID: 26791948
Systemic Candida albicans infection causes high morbidity and mortality and is now the leading cause of nosocomial bloodstream infection in the United States. Neutropenia is a major risk factor for...
3.
Nundel K, Green N, Shaffer A, Moody K, Busto P, Eilat D, et al.
J Immunol
. 2015 Feb;
194(6):2504-12.
PMID: 25681333
Endosomal TLRs play an important role in systemic autoimmune diseases, such as systemic erythematosus lupus, in which DNA- and RNA-associated autoantigens activate autoreactive B cells through TLR9- and TLR7-dependent pathways....
4.
Lionakis M, Swamydas M, Fischer B, Plantinga T, Johnson M, Jaeger M, et al.
J Clin Invest
. 2013 Nov;
123(12):5035-51.
PMID: 24177428
Systemic Candida albicans infection causes high morbidity and mortality and is associated with neutropenia; however, the roles of other innate immune cells in pathogenesis are poorly defined. Here, using a...
5.
Green N, Moody K, Debatis M, Marshak-Rothstein A
J Biol Chem
. 2012 Sep;
287(47):39789-99.
PMID: 23019335
The key step in the activation of autoreactive B cells is the internalization of nucleic acid containing ligands and delivery of these ligands to the Toll-like Receptor (TLR) containing endolysosomal...
6.
Green N, Marshak-Rothstein A
Semin Immunol
. 2011 Feb;
23(2):106-12.
PMID: 21306913
Studies over the past decade have demonstrated a key role for pattern recognition receptors in the activation of autoreactive B cells. Self reactive B cells that manage to escape negative...
7.
Green N, Laws A, Kiefer K, Busconi L, Kim Y, Brinkmann M, et al.
J Immunol
. 2009 Jul;
183(3):1569-76.
PMID: 19587008
Type I IFNs play an important, yet poorly characterized, role in systemic lupus erythematosus. To better understand the interplay between type I IFNs and the activation of autoreactive B cells,...
8.
Uccellini M, Busconi L, Green N, Busto P, Christensen S, Shlomchik M, et al.
J Immunol
. 2008 Oct;
181(9):5875-84.
PMID: 18941176
Autoreactive B cells are activated by DNA, chromatin, or chromatin-containing immune complexes (ICs) through a mechanism dependent on dual engagement of the BCR and TLR9. We examined the contribution of...
9.
Overheim K, DePaolo R, DeBord K, Morrin E, Anderson D, Green N, et al.
Infect Immun
. 2005 Jul;
73(8):5152-9.
PMID: 16041032
Yersinia pestis, the causative agent of plague, secretes LcrV (low-calcium-response V or V antigen) during infection. LcrV triggers the release of interleukin 10 (IL-10) by host immune cells and suppresses...