N Neamati
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Explore the profile of N Neamati including associated specialties, affiliations and a list of published articles.
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44
Citations
561
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Recent Articles
1.
Dual inhibition of survivin and MAOA synergistically impairs growth of PTEN-negative prostate cancer
Xu S, Adisetiyo H, Tamura S, Grande F, Garofalo A, Roy-Burman P, et al.
Br J Cancer
. 2015 Jun;
113(2):242-51.
PMID: 26103574
Background: Survivin and monoamine oxidase A (MAOA) levels are elevated in prostate cancer (PCa) compared to normal prostate glands. However, the relationship between survivin and MAOA in PCa is unclear....
2.
Mazumder A, Neamati N, Sunder S, Owen J, Pommier Y
Methods Mol Med
. 2011 Feb;
24:327-38.
PMID: 21331920
Two critical events are the signature of the life cycle of retroviruses (1). The first is reverse transcription, whereby the single-stranded RNA genome of the retrovirus is copied into double-stranded...
3.
Aiello F, Brizzi A, De Grazia O, Garofalo A, Grande F, Sinicropi M, et al.
Eur J Med Chem
. 2006 Jun;
41(8):914-7.
PMID: 16781021
Herein, we describe a new strategy for the preparation of thiazolothiazepine-based inhibitors of human immunodeficiency virus type-1 integrase (IN). The present method allows facile preparation of the title compounds in...
4.
Plasencia C, Martinez-Balibrea E, Martinez-Cardus A, Quinn D, Abad A, Neamati N
Int J Oncol
. 2006 Jun;
29(1):225-35.
PMID: 16773204
The interrelationship between platinum resistance and clinical response is not well established. The purpose of this study is to evaluate the expression of 14 genes involved in platinum resistance in...
5.
Neamati N
Expert Opin Investig Drugs
. 2002 Jan;
10(9):1767-70.
PMID: 11785455
No abstract available.
6.
Marchand C, Neamati N, Pommier Y
Methods Enzymol
. 2001 Aug;
340:624-33.
PMID: 11494874
No abstract available.
7.
Zhang X, Neamati N, Lee Y, Orr A, Brown R, Whitaker N, et al.
Bioorg Med Chem
. 2001 Jun;
9(7):1649-57.
PMID: 11425564
Integrase is an enzyme found in human immunodeficiency virus, which is required for the viral life cycle, yet has no human cellular homologue. For this reason, HIV integrase (IN) has...
8.
Taktakishvili M, Neamati N, Pommier Y, Nair V
Bioorg Med Chem Lett
. 2001 May;
11(11):1433-5.
PMID: 11378371
Integration of HIV viral DNA into human chromosomal DNA catalyzed by HIV integrase is essential for the replication of HIV. Discovery of novel inhibitors of HIV integrase is of considerable...
9.
Neamati N
Expert Opin Investig Drugs
. 2001 Feb;
10(2):281-96.
PMID: 11178341
The pol gene of HIV-1 encodes for three essential enzymes, protease (PR), reverse transcriptase (RT) and integrase (IN). More than 16 drugs, targeting two of these enzymes, PR and RT...
10.
Chen I, Neamati N, Nicklaus M, Orr A, Anderson L, Barchi Jr J, et al.
Bioorg Med Chem
. 2000 Nov;
8(10):2385-98.
PMID: 11058033
Integration of viral DNA into the host cell genome is a critical step in the life cycle of HIV. This essential reaction is catalyzed by integrase (IN) through two steps,...