N C Luetteke
Overview
Explore the profile of N C Luetteke including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
948
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Recent Articles
1.
Troyer K, Luetteke N, Saxon M, Qiu T, Xian C, Lee D
Gastroenterology
. 2001 Jul;
121(1):68-78.
PMID: 11438495
Background And Aims: Mice lacking epidermal growth factor (EGF), transforming growth factor alpha, and amphiregulin were used to identify roles for these EGF receptor (EGF-R) ligands in gastrointestinal development and...
2.
Luetteke N, Qiu T, Fenton S, Troyer K, Riedel R, Chang A, et al.
Development
. 1999 May;
126(12):2739-50.
PMID: 10331984
Targeted mice lacking functional EGF or amphiregulin (AR) were derived and bred to the TGFalpha-knockout to generate mice lacking various combinations of the three ligands. In contrast to EGF receptor...
3.
Carroll J, Luetteke N, Lee D, Watt F
Mech Dev
. 1998 Dec;
78(1-2):37-45.
PMID: 9858678
Eyelid fusion normally occurs between E15.5 and E16.5 of mouse embryonic development and results from the migration of a population of periderm-derived epithelial cells over the corneal surface. Cell migration...
4.
Humble M, Szczesniak C, Luetteke N, Spalding J, Cannon R, Hansen L, et al.
Toxicol Pathol
. 1998 Aug;
26(4):562-9.
PMID: 9715516
Alterations in growth factor signaling pathways frequently accompany the development and maintenance of epithelial neoplasia. Transforming growth factor alpha (TGF alpha) and its epidermal growth factor receptor have been thought...
5.
Berkowitz E, Seroogy K, Schroeder J, RUSSELL W, Evans E, Riedel R, et al.
Cell Growth Differ
. 1996 Sep;
7(9):1271-82.
PMID: 8877107
The spontaneous mouse waved 1 (wa1) mutation is allelic with the transforming growth factor alpha (TGF-alpha) gene and produces phenotypes similar to those of TGF-alpha knockout mice. Here, we show...
6.
RUSSELL W, Kaufmann W, Sitaric S, Luetteke N, Lee D
Mol Carcinog
. 1996 Mar;
15(3):183-9.
PMID: 8597531
Transforming growth factor-alpha (TGF alpha), a member of the epidermal growth factor receptor ligand family, has been implicated in the regeneration and transformation of liver. Our recent development of mice...
7.
Pathak B, Gilbert D, Harrison C, Luetteke N, Chen X, Klagsbrun M, et al.
Genomics
. 1995 Jul;
28(1):116-8.
PMID: 7590736
The products of five distinct loci, Egf, Tgfa, Areg, Btc, and Hegfl act as ligands for the epidermal growth factor receptor. Egf and Tgfa have previously been mapped to mouse...
8.
Luetteke N, Phillips H, Qiu T, Copeland N, Earp H, Jenkins N, et al.
Genes Dev
. 1994 Feb;
8(4):399-413.
PMID: 8125255
Mice harboring the waved-1 (wa-1) and waved-2 (wa-2) mutations exhibit skin and eye abnormalities that are strikingly similar to those of TGF-alpha-deficient mice, and wa-1 and TGF-alpha were recently shown...
9.
Luetteke N, Qiu T, Peiffer R, Oliver P, SMITHIES O, Lee D
Cell
. 1993 Apr;
73(2):263-78.
PMID: 8477445
To explore the physiological roles of transforming growth factor alpha (TGF alpha), we disrupted the mouse gene by homologous recombination in embryonic stem cells. Homozygous mutant mice were viable and...
10.
Luetteke N, Lee D, Palmiter R, Brinster R, Sandgren E
Cell Growth Differ
. 1993 Mar;
4(3):203-13.
PMID: 8466858
Transgenic mice overexpressing transforming growth factor alpha (TGF-alpha) under control of the metallothionein promoter had, on average, 20% reductions in body and carcass weights compared to nontransgenic littermates. This loss...